4'-Thiothymidine

4'-Thiothymidine

SCHEMBL3517583

Cc1cn([C@H]2C[C@@H](O)[C@@H](CO)S2)c(=O)[nH]c1=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
ALB P02768 1/20 0.49
POLB P06746 1/20 0.49
ADRA1A P35348 1/20 0.49
BLM P54132 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4'-Thiothymidine SCHEMBL6266871 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL1942500 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL13083838 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL23897578 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL6311407 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL23897630 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL3517588 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL9520953 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL12642446 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB
4'-Thiothymidine SCHEMBL30381070 1.00 TK1 (0.49) TK1ALDH1A1LMNAALBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021202788-A2 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2021-10-07 WO disclosed
US-20120225837-A1 MEDICINAL AGENT FOR DISEASE ASSOCIATED WITH EPSTEIN-BARR VIRUS, AND METHOD FOR SCREENING OF THE MEDICINAL AGENT KYOTO UNIVERSITY (JP) 2012-09-06 US disclosed
EP-2189161-B1 MEDICINAL AGENT FOR DISEASE ASSOCIATED WITH EPSTEIN-BARR VIRUS, AND METHOD FOR SCREENING OF THE MEDICINAL AGENT YAMASA CORP (JP) 2012-08-08 EP disclosed
US-20100330563-A1 MEDICINAL AGENT FOR DISEASE ASSOCIATED WITH EPSTEIN-BARR VIRUS, AND METHOD FOR SCREENING OF THE MEDICINAL AGENT YAMASA CORPORATION (JP) 2010-12-30 US disclosed
EP-2189161-A1 MEDICINAL AGENT FOR DISEASE ASSOCIATED WITH EPSTEIN-BARR VIRUS, AND METHOD FOR SCREENING OF THE MEDICINAL AGENT YAMASA CORPORATION (JP) 2010-05-26 EP disclosed