Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852998 | 0.92 | NPC1 (0.59) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL4456501 | 0.78 | HIF1A (0.53) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL4456375 | 0.72 | P2RX7 (0.55) | HPGDPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL3225126 | 0.71 | NPC1 (1.00) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL2855548 | 0.71 | CCR1 (0.68) | HPGDMEN1GAAKMT2A | |
| SCHEMBL8636926 | 0.71 | NPC1 (0.70) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL10367016 | 0.70 | NPC1 (0.54) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL937958 | 0.69 | NPC1 (0.57) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL11192370 | 0.69 | MAPK14 (0.59) | SMN1; SMN2HPGDPOLBALDH1A1TSHR | |
| SCHEMBL6275666 | 0.69 | HPGD (0.59) | HPGDPOLBALDH1A1TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283349-B2 | Fungicide N-(3-phenylpropyl) carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-10-09 | — | — | US | claimed |
| US-20100087494-A1 | FUNGICIDE N-(3-PHENYLPROPYL) CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-04-08 | — | — | US | claimed |
| EP-2125740-A1 | FUNGICIDE N-(3-PHENYLPROPYL)CARBOXAMIDE DERIVATIVES | Bayer CropScience SA (FR) | 2009-12-02 | — | — | EP | claimed |
| WO-2008101976-A1 | FUNGICIDE N-(3-PHENYLPROPYL)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-08-28 | — | — | WO | claimed |
| US-8283349-B2 | Fungicide N-(3-phenylpropyl) carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-10-09 | — | — | US | disclosed |
| US-20100087494-A1 | FUNGICIDE N-(3-PHENYLPROPYL) CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-04-08 | — | — | US | disclosed |
| EP-2125740-A1 | FUNGICIDE N-(3-PHENYLPROPYL)CARBOXAMIDE DERIVATIVES | Bayer CropScience SA (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008101976-A1 | FUNGICIDE N-(3-PHENYLPROPYL)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087494-A1 | FUNGICIDE N-(3-PHENYLPROPYL) CARBOXAMIDE DERIVATIVES | CYP51A1, CYP1A2, CYP3A7 | SMN1; SMN2 2779/4885HPGD 2749/4885NPC1 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.