Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.44 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852998 | 0.82 | NPC1 (0.59) | HIF1ANPC1RAB9AKMT2ACNR1 | |
| SCHEMBL4456375 | 0.78 | P2RX7 (0.55) | MEN1KMT2ACNR1LMNAHPGD | |
| SCHEMBL3520114 | 0.78 | SMN1; SMN2 (0.58) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL31683861 | 0.74 | NPC1 (0.53) | HIF1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28635599 | 0.74 | NPC1 (0.53) | HIF1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28588186 | 0.72 | P2RX7 (0.53) | HIF1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL937246 | 0.71 | HIF1A (0.62) | HIF1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL1010476 | 0.71 | MTNR1A (0.61) | HIF1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL2857899 | 0.71 | KLKB1 (0.56) | HIF1ARAB9ALMNAHPGDTRPV1 | |
| SCHEMBL1412850 | 0.70 | P2RX7 (0.84) | HIF1AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954674-B1 | NEW N-PHENETHYLCARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-03-16 | — | — | EP | claimed |
| US-20090170924-A1 | N-Phenethylcarboxamide Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-07-02 | — | — | US | claimed |
| EP-1954674-A1 | NEW N-PHENETHYLCARBOXAMIDE DERIVATIVES | Bayer CropScience S.A. (FR) | 2008-08-13 | — | — | EP | claimed |
| WO-2007060166-A1 | NEW N-PHENETHYLCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-05-31 | — | — | WO | claimed |
| EP-1787981-A1 | New N-phenethylcarboxamide derivatives | Bayer CropScience S.A. (FR) | 2007-05-23 | — | — | EP | claimed |
| US-9440946-B2 | N-phenethylcarboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-13 | — | — | US | disclosed |
| EP-1954674-B1 | NEW N-PHENETHYLCARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-20090170924-A1 | N-Phenethylcarboxamide Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| EP-1954674-A1 | NEW N-PHENETHYLCARBOXAMIDE DERIVATIVES | Bayer CropScience S.A. (FR) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007060166-A1 | NEW N-PHENETHYLCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-05-31 | — | — | WO | disclosed |
| EP-1787981-A1 | New N-phenethylcarboxamide derivatives | Bayer CropScience S.A. (FR) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170924-A1 | N-Phenethylcarboxamide Derivatives | GANC, KCNH1, GANAB | HIF1A 1612/4885NPC1 185/4885RAB9A 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.