SCHEMBL3521279

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9779798	0.74	TSHR (0.50)	TSHRSMN1; SMN2ROCK2ALDH1A1LMNA
	SCHEMBL10844281	0.74	TSHR (0.50)	TSHRSMN1; SMN2ROCK2ALDH1A1MEN1
	SCHEMBL3523570	0.72	L3MBTL1 (0.71)	SMN1; SMN2ROCK2ALDH1A1LMNAL3MBTL1
	SCHEMBL14507901	0.71	TP53 (0.57)	DHFRTP53HBBSMN1; SMN2ALDH1A1
	SCHEMBL10523507	0.71	TP53 (0.47)	TSHRDHFRTP53HBBSMN1; SMN2
	SCHEMBL1715940	0.71	TP53 (0.62)	DHFRTP53HBBSMN1; SMN2ALDH1A1
	SCHEMBL18432812	0.71	ALDH1A1 (0.47)	TSHRTP53SMN1; SMN2ROCK2ALDH1A1
	SCHEMBL7981665	0.71	ALDH1A1 (0.39)	TSHRDHFRTP53SMN1; SMN2ALDH1A1
	SCHEMBL8335732	0.70	ADRB2 (0.43)	TSHRROCK2ALDH1A1LMNAL3MBTL1
	SCHEMBL5821147	0.69	ALDH1A1 (0.56)	DHFRSMN1; SMN2ALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.