Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844281 | 0.81 | TSHR (0.50) | TSHRROCK2ALDH1A1IDO1PKM | |
| SCHEMBL18432812 | 0.79 | ALDH1A1 (0.47) | TSHRROCK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7305862 | 0.78 | TSHR (0.63) | TSHRROCK2ALDH1A1PKMHTT | |
| SCHEMBL3521279 | 0.74 | TSHR (0.43) | TSHRROCK2ALDH1A1IDO1PKM | |
| SCHEMBL4670086 | 0.74 | ROCK2 (0.61) | TSHRROCK2IDO1TDO2SMN1; SMN2 | |
| SCHEMBL9779829 | 0.71 | ROCK2 (0.47) | TSHRROCK2ALDH1A1IDO1TDO2 | |
| SCHEMBL8301872 | 0.71 | ALDH1A1 (0.51) | TSHRALDH1A1IDO1PKMTDO2 | |
| SCHEMBL8335732 | 0.71 | ADRB2 (0.43) | TSHRROCK2ALDH1A1HTTHPGD | |
| SCHEMBL14600368 | 0.70 | ROCK2 (0.49) | TSHRROCK2ALDH1A1IDO1PKM | |
| SCHEMBL4670084 | 0.70 | ROCK2 (0.56) | TSHRROCK2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049554-A | Phosphorous substituted tetrazolinones and insecticidal use thereof | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0145328-B1 | SUBSTITUTED TETRAZOLINONES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1990-05-16 | — | — | EP | disclosed |
| EP-0145328-A2 | Substituted tetrazolinones | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1985-06-19 | — | — | EP | disclosed |