Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779798 | 0.81 | TSHR (0.50) | TSHRROCK2ALDH1A1PKMIDO1 | |
| SCHEMBL18432812 | 0.79 | ALDH1A1 (0.47) | TSHRROCK2ALDH1A1GSK3AGSK3B | |
| SCHEMBL10840968 | 0.74 | IDO1 (0.49) | TSHRROCK2ALDH1A1IDO1TDO2 | |
| SCHEMBL3521279 | 0.74 | TSHR (0.43) | TSHRROCK2ALDH1A1PKMIDO1 | |
| SCHEMBL8301872 | 0.71 | ALDH1A1 (0.51) | TSHRALDH1A1PKMIDO1TDO2 | |
| SCHEMBL8335732 | 0.71 | ADRB2 (0.43) | TSHRROCK2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL4670086 | 0.70 | ROCK2 (0.61) | TSHRROCK2IDO1TDO2CYP1A2 | |
| SCHEMBL14600368 | 0.67 | ROCK2 (0.49) | TSHRROCK2ALDH1A1PKMIDO1 | |
| SCHEMBL4670084 | 0.66 | ROCK2 (0.56) | TSHRROCK2ALDH1A1MEN1KMT2A | |
| SCHEMBL4675660 | 0.66 | ROCK2 (0.56) | ROCK2ALDH1A1PKMIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584303-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0160422-A1 | N-Aryl-N-(4-Piperidinyl)amides and pharmaceutical compositions and methods employing such compounds | Anaquest, Inc. (US) | 1985-11-06 | — | — | EP | disclosed |