Glutamine

Glutamine

SCHEMBL352340

NC(=O)CCC(N)C(=O)O.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PMP22 Q01453 2/20 0.86
ALOX15 P16050 1/20 0.86
BLM P54132 1/20 0.86
KMT2A Q03164 1/20 0.86
GRM8 O00222 2/20 0.82
GRM6 O15303 2/20 0.82
GRM7 Q14831 2/20 0.82
GRM4 Q14833 2/20 0.82
GRIN2D O15399 1/20 0.82
GRIN3B O60391 1/20 0.82
GSR P00390 1/20 0.82
CYP1A2 P05177 1/20 0.82
GRIK1 P39086 1/20 0.82
GRM5 P41594 1/20 0.82
GRIA1 P42261 1/20 0.82
GRIA2 P42262 1/20 0.82
GRIA3 P42263 1/20 0.82
SLC1A3 P43003 1/20 0.82
SLC1A2 P43004 1/20 0.82
SLC1A1 P43005 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL9165715 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL9276090 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL19878277 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL9276094 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL352341 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL1634485 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL8429219 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL2443861 1.00 PMP22 (0.86) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL28971512 0.98 PMP22 (0.83) PMP22ALOX15BLMKMT2AGRM8
Glutamine SCHEMBL28756768 0.94 ALOX15 (0.76) PMP22ALOX15BLMKMT2AGRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110542731-B Fingerprint detection method of white ginseng fungus 湖南宇山玉月农业科技有限公司 2022-05-17 CN claimed
CN-108949826-A The recombined glandulae correlation viral vectors and its construction method of carrying MAGE-A3 mutant antigen gene and application 北京安斯晨睿生物科技有限公司 2018-12-07 CN claimed
US-20150273088-A1 ZAPRINAST ANALOGUES AS GLUTAMINASE INHIBITORS AND METHODS TO PREDICT RESPONSE THERETO WASHINGTON UNIVERSITY (US) 2015-10-01 US claimed
WO-2003002135-A2 HERBAL COMPOSITION PRETORIUS ANDRIES PHILIPPUS (ZA) 2003-01-09 WO claimed
EP-0514509-B1 COMPOSITION AND ITS PREPARATION PROCESS USING ANTIGEN CONJUGATED TO ENZYMATIC ACTIVITY FOR IMMUNOLOGICAL DIAGNOSIS AND CHAGAS' DISEASE IMMUNOLOGICAL DIAGNOSIS KITS, FOR INDIVIDUAL AND EPIDEMIOLOGICAL APPLICATION, BASED ON THAT COMPOSITION FUNDACAO OSWALDO CRUZ (BR) 2000-09-20 EP claimed
US-4225614-A Method of treatment for mucocutaneous herpes simplex infections AKTIEBOLAGET DRACO (SE) 1980-09-30 US claimed
US-12583896-B2 Caged-degron-based molecular feedback circuits and methods of using the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-24 US disclosed
US-12016869-B2 Dairy product and process FONTERRA CO-OPERATIVE GROUP LIMITED (NZ) 2024-06-25 US disclosed
US-20240201296-A1 Magnetic Resonance Spectroscopy Frequency and Phase Correction THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-06-20 US disclosed
US-20240165070-A1 GLUTAMINASE INHIBITOR THERAPY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-05-23 US disclosed
CN-118028131-A Microecological preparation product for simultaneously improving depression or anxiety and sleep 浙江妙活氏生物科技有限公司 2024-05-14 CN disclosed
US-20240115566-A1 METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR ST JUDE CHILDRENS RES HOSPITAL INC (US) 2024-04-11 US disclosed
CN-116973575-A Application of biomarker in preparation of kit for detecting Du's muscular dystrophy carrier 南京市妇幼保健院 2023-10-31 CN disclosed
WO-1993013794-A1 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORPORATION (US) 1993-07-22 WO disclosed
US-5223638-A Reacting primary or secondary amine with carbon dioxide in presence of strong amidine or guanidine base to form ammonium carbamate salt, reacting in polar aprotic solvent with primary or secondary hydrocarbyl halide MONSANTO COMPANY (US) 1993-06-29 US disclosed
EP-0535088-A1 CHIMERIC TOXINS WITH IMPROVED INTER-DOMAIN GEOMETRY THE UNIVERSITY HOSPITAL (US) 1993-04-07 EP disclosed
CN-1069735-A The synthetic fast and screening of peptide mimics LILLY CO ELI (US) 1993-03-10 CN disclosed
EP-0511948-A2 Preparation of urethane and carbonate products MONSANTO COMPANY (US) 1992-11-04 EP disclosed
WO-1991019745-A1 CHIMERIC TOXINS WITH IMPROVED INTER-DOMAIN GEOMETRY THE UNIVERSITY HOSPITAL (US) 1991-12-26 WO disclosed
EP-0035831-B1 METHOD FOR MAKING GENETICALLY MODIFIED MICROORGANISMS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165070-A1 GLUTAMINASE INHIBITOR THERAPY ASNS, GLS, GLS2 PMP22 3456/4885ALOX15 1241/4885BLM 3384/4885
US-20150273088-A1 ZAPRINAST ANALOGUES AS GLUTAMINASE INHIBITORS AND METHODS TO PREDICT RESPONSE THERETO GLS, GLS2, GLUL PMP22 3150/4885ALOX15 3000/4885BLM 1913/4885
US-12583896-B2 Caged-degron-based molecular feedback circuits and methods of using the same RPRD2, STUB1, SSU72 PMP22 4594/4885ALOX15 4749/4885BLM 586/4885
US-20240115566-A1 METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR HMGCR, GCDH, ACADM PMP22 255/4885ALOX15 1505/4885BLM 4426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.