SCHEMBL352637

SCHEMBL352637

C=C(C(=O)OCOC(C)=O)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
THRB P10828 1/20 0.31
PGR P06401 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
HTR1A P08908 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRM3 P20309 1/20 0.30
TBXA2R P21731 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2625617 0.78 TSHR (0.52) ALDH1A1HSD17B10LMNATSHRTDP1
SCHEMBL9313077 0.77 ALDH1A1 (0.50) ALDH1A1HSD17B10LMNATSHRTDP1
SCHEMBL1896769 0.76 ALDH1A1 (0.48) ALDH1A1HSD17B10LMNATSHRTHRB
SCHEMBL22545152 0.75 THRB (0.57) ALDH1A1TSHRTDP1THRB
SCHEMBL28791986 0.74 TSHR (0.44) ALDH1A1TSHRTDP1THRB
SCHEMBL8744223 0.74 ALDH1A1 (0.47) ALDH1A1HSD17B10LMNATSHRTHRB
SCHEMBL8990044 0.74 TSHR (0.30) TSHR
SCHEMBL29117402 0.74 TSHR (0.30) TSHR
SCHEMBL322669 0.74
SCHEMBL351308 0.73 TDP1 (0.33) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2415751-B1 ALPHA-(UNSATURATED ALKOXYALKYL) ACRYLATE COMPOSITION AND PROCESS FOR PRODUCTION THEREOF NIPPON CATALYTIC CHEM IND (JP) 2014-11-26 EP disclosed
US-8796492-B2 α-(unsaturated alkoxyalkyl) acrylate composition and process for production thereof NIPPON SHOKUBAI CO., LTD. (JP) 2014-08-05 US disclosed
EP-2415751-A1 ALPHA-(UNSATURATED ALKOXYALKYL) ACRYLATE COMPOSITION AND PROCESS FOR PRODUCTION THEREOF Nippon Shokubai Co., Ltd. (JP) 2012-02-08 EP disclosed
US-20120016095-A1 a-(UNSATURATED ALKOXYALKYL) ACRYLATE COMPOSITION AND PROCESS FOR PRODUCTION THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 2012-01-19 US disclosed