Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND1 | P24385 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528315 | 0.90 | NOTUM (0.43) | CDK4CCND1ALDH1A1NAMPTRAB9A | |
| SCHEMBL3524858 | 0.85 | PDK2 (0.42) | NAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL169287 | 0.79 | NOTUM (0.42) | ALDH1A1NAMPTRAB9ANPC1HTT | |
| SCHEMBL3533607 | 0.75 | KMT2A (0.42) | ALDH1A1RAB9ANPC1NPSR1HPGD | |
| SCHEMBL16104413 | 0.75 | RAB9A (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL20439976 | 0.71 | POLB (0.50) | CDK4CCND1ALDH1A1PTGS1PTGDR2 | |
| SCHEMBL10211721 | 0.71 | HPGD (0.56) | ALDH1A1NAMPTPTGDR2NPSR1HPGD | |
| SCHEMBL20425836 | 0.69 | HPGD (0.48) | ALDH1A1PTGS1RAB9APTGDR2HPGD | |
| SCHEMBL20439762 | 0.68 | PTGS1 (0.46) | CDK4CCND1ALDH1A1NAMPTPTGS1 | |
| SCHEMBL14591322 | 0.67 | PTGDR2 (0.58) | ALDH1A1NAMPTPTGDR2NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101115-A1 | Compounds For Inducing Cellular Apoptosis | QUEEN MARY AND WESTFIELD COLLEGE (GB) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101115-A1 | Compounds For Inducing Cellular Apoptosis | BAD, BAX, CASP3 | CDK4 53/4885CCND1 320/4885ALDH1A1 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.