Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.46 |
| ▸ | CA1 | P00915 | 15/20 | 0.46 |
| ▸ | CA9 | Q16790 | 11/20 | 0.46 |
| ▸ | CA3 | P07451 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536209 | 0.81 | CYP3A4 (0.39) | CA2CA1CA9CA3CA12 | |
| SCHEMBL1497205 | 0.80 | CA1 (0.59) | CA2CA1CA9CA3CA12 | |
| SCHEMBL20421466 | 0.79 | CA2 (0.50) | CA2CA1CA9CA3CA12 | |
| SCHEMBL283890 | 0.78 | CYP3A4 (0.56) | CA2CA1CA9CA3CA12 | |
| SCHEMBL3110388 | 0.78 | CA2 (0.56) | CA2CA1CA9CA3CA12 | |
| SCHEMBL3918873 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL2535181 | 0.74 | ALDH1A1 (0.42) | CA2CA9CA12CA4ALDH1A1 | |
| SCHEMBL671650 | 0.72 | KDM4E (0.48) | CA2CA1CA4CYP2C19ALDH1A1 | |
| SCHEMBL31487920 | 0.72 | CA2 (0.68) | CA2CA1CA9CA3CA12 | |
| SCHEMBL30739727 | 0.72 | KDM4E (0.48) | CA2CA1CA4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725467-B2 | Fluorinated benzenesulfonamides as inhibitors of carbonic anhydrase | VILNIUS UNIVERSITY (LT) | 2017-08-08 | — | — | US | disclosed |
| US-20150266900-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | VILNIUS UNIVERSITY (LT) | 2015-09-24 | — | — | US | disclosed |
| EP-2914583-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | Vilnius University (LT) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014062044-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | VILNIUS UNIVERSITY (LT) | 2014-04-24 | — | — | WO | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20060229336-A1 | Ccr5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORPORATION | 2006-10-12 | — | — | US | disclosed |
| EP-1569646-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004054974-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266900-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | CA9, CA7, CA2 | CA2 3/4885CA1 7/4885CA9 1/4885 |
| US-20060229336-A1 | Ccr5 antagonists as therapeutic agents | CCR5, CCR1, CXCR3 | CA2 4267/4885CA1 4808/4885CA9 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.