SCHEMBL353271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL766883	0.81	PHGDH (0.48)	CNR2CNR1MMP1AKR1C3MMP2
	SCHEMBL1464410	0.80	CA1 (0.54)	CNR2MMP1MMP2MMP9MMP13
	SCHEMBL1464762	0.79	ALDH1A1 (0.47)	MMP1MMP2MMP9MMP13ALDH1A1
	SCHEMBL2227158	0.79	ENPP2 (0.48)	AKR1C3
	SCHEMBL10147798	0.79	ALDH1A1 (0.69)	CNR2CNR1MMP1MMP2MMP3
	SCHEMBL1464395	0.79	HSD11B1 (0.48)	MMP1MMP2MMP9MMP13ALDH1A1
	SCHEMBL1463945	0.78	TRPV4 (0.42)	CNR2CNR1TRPV4
	SCHEMBL17908079	0.78	CA2 (0.52)	ALDH1A1CA12CA1CA2CA9
	SCHEMBL352118	0.78	CNR2 (0.52)	CNR2CNR1MMP2MMP9ALDH1A1
	SCHEMBL1464602	0.78	CNR2 (0.50)	CNR2CNR1MMP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.