Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22518511 | 0.83 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL2061609 | 0.79 | MAPK14 (0.44) | NPC1RAB9ASMN1; SMN2BAZ2BSPR | |
| SCHEMBL1663553 | 0.78 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2SPRLMNA | |
| SCHEMBL1641560 | 0.78 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL10184712 | 0.77 | KMT2A (0.53) | NPC1RAB9ASMN1; SMN2SPRLMNA | |
| SCHEMBL17993521 | 0.77 | SPR (0.45) | NPC1RAB9ASMN1; SMN2BAZ2BSPR | |
| Hydrochloric Acid SCHEMBL17995092 | 0.76 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2SPRLMNA | |
| SCHEMBL6397435 | 0.76 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL3050197 | 0.76 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL353360 | 0.75 | MET (0.46) | NPC1RAB9ASMN1; SMN2BAZ2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | NPC1 3444/4885RAB9A 1714/4885SMN1; SMN2 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.