SCHEMBL3534341

SCHEMBL3534341

Cc1nc2cc(B3OC(C)(C)C(C)(C)O3)ccc2o1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
GAA P10253 1/20 0.46
LPL P06858 8/20 0.41
LIPG Q9Y5X9 8/20 0.41
RAB9A P51151 4/20 0.40
NPC1 O15118 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
IRAK4 Q9NWZ3 1/20 0.40
STAT1 P42224 1/20 0.40
CSF1R P07333 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
IDO1 P14902 1/20 0.37
TDO2 P48775 1/20 0.37
SNCA P37840 1/20 0.37
EGFR P00533 2/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13718340 0.88 LPL (0.41) L3MBTL1GAALPLLIPGSMN1; SMN2
SCHEMBL2724794 0.83 LMNA (0.49) LPLLIPGIRAK4MAPTSNCA
SCHEMBL29867543 0.83 LMNA (0.49) LPLLIPGIRAK4MAPTSNCA
SCHEMBL22160380 0.81 LPL (0.41) LPLLIPGRAB9ANPC1IRAK4
SCHEMBL10173049 0.81 NPC1 (0.51) L3MBTL1LPLLIPGRAB9ANPC1
SCHEMBL30106845 0.80 GAA (0.40) GAALPLLIPGIRAK4MEN1
SCHEMBL3262084 0.79 NPC1 (0.57) L3MBTL1LPLLIPGRAB9ANPC1
SCHEMBL24772933 0.77 LPL (0.36) GAALPLLIPGIRAK4MEN1
SCHEMBL22298363 0.77 SNCA (0.40) GAALPLLIPGCSF1RMEN1
SCHEMBL24479513 0.77 LPL (0.42) L3MBTL1LPLLIPGRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-12304907-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-05-20 US disclosed
US-12264154-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-04-01 US disclosed
EP-4477656-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-12-18 EP disclosed
US-20240368173-A1 TRICYCLIC GPR65 MODULATORS Pathios Therapeutics Limited (GB) 2024-11-07 US disclosed
US-20240349591-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-10-17 US disclosed
US-12116369-B2 Substituted pyrazolo[1,5-a]pyrimidines as glucocerebrosidase activators Bial—R&D Investments, S.A. (PT) 2024-10-15 US disclosed
EP-4419203-A1 TRICYCLIC GPR65 MODULATORS Pathios Therapeutics Limited (GB) 2024-08-28 EP disclosed
US-20240279219-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2024-08-22 US disclosed
US-20240228478-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2024-07-11 US disclosed
WO-2013014165-A1 SUBSTITUTED PICOLINIC ACIDS AND PYRIMIDINE-4-CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-01-31 WO disclosed
US-8273736-B2 Thienopyridine and furopyridine kinase inhibitors ABBOTT LABORATORIES (US) 2012-09-25 US disclosed
US-7737160-B2 Thienopyridine and furopyridine kinase inhibitors ABBOTT LABORATORIES INC. (US) 2010-06-15 US disclosed
US-20100069371-A1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS ABBOTT LABORATORIES (US) 2010-03-18 US disclosed
EP-1648905-B1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS ABBOTT LAB (US) 2008-12-31 EP disclosed
US-20070155776-A1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS ABBVIE INC. 2007-07-05 US disclosed
US-7202363-B2 Thienopyridine and furopyridine kinase inhibitors ABBOTT LABORATORIES (US) 2007-04-10 US disclosed
EP-1648905-A1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS Abbott Laboratories (US) 2006-04-26 EP disclosed
US-20050043347-A1 Thienopyridine and furopyridine kinase inhibitors ABBVIE INC. 2005-02-24 US disclosed
WO-2005010009-A1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS ABBOTT LABORATORIES (US) 2005-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240349591-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, OCIAD1, OCIAD2 L3MBTL1 535/4885GAA 3960/4885LPL 342/4885
US-12116369-B2 Substituted pyrazolo[1,5-a]pyrimidines as glucocerebrosidase activators GBA1, GALC, GBA3 L3MBTL1 3630/4885GAA 4/4885LPL 295/4885
US-20240368173-A1 TRICYCLIC GPR65 MODULATORS GPR65, GPR3, NR1H2 L3MBTL1 4129/4885GAA 4385/4885LPL 1411/4885
US-20240279219-A1 COMPOUNDS AND METHODS OF USE F12, C1R, ABCG2 L3MBTL1 3066/4885GAA 889/4885LPL 2221/4885
US-12264154-B2 Compounds and methods of use F12, C1R, ABCG2 L3MBTL1 3066/4885GAA 889/4885LPL 2221/4885
US-20050043347-A1 Thienopyridine and furopyridine kinase inhibitors ABL1, ERBB2, LCK L3MBTL1 4181/4885GAA 2970/4885LPL 4579/4885
US-20100069371-A1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS ABL1, ERBB2, LCK L3MBTL1 4181/4885GAA 2970/4885LPL 4579/4885
US-12304907-B2 Compounds and methods of use F12, C1R, ABCG2 L3MBTL1 3066/4885GAA 889/4885LPL 2221/4885
US-20240228478-A1 COMPOUNDS AND METHODS OF USE F12, C1R, ABCG2 L3MBTL1 3066/4885GAA 889/4885LPL 2221/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 L3MBTL1 3444/4885GAA 2519/4885LPL 1131/4885
US-20070155776-A1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS ABL1, ERBB2, LCK L3MBTL1 4181/4885GAA 2970/4885LPL 4579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.