SCHEMBL353584

SCHEMBL353584

CCOC(=O)C(=O)c1csc(N)n1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.69
MAPT P10636 5/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
NPC1 O15118 2/20 0.69
RAB9A P51151 2/20 0.69
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MAPK1 P28482 2/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 2/20 0.45
PKM P14618 2/20 0.45
KDM4E B2RXH2 1/20 0.45
TSHR P16473 2/20 0.44
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NOS1 P29475 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRB2 P47870 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11009689 0.98 ALDH1A1 (0.72) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL22755660 0.88 MAPT (0.57) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL13451814 0.83 MAPT (0.47) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL220846 0.83 RAB9A (0.97) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL10464683 0.83 ALDH1A1 (0.52) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL11184434 0.83 MAPT (0.68) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL7107470 0.83 MAPT (0.68) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL7107465 0.83 MAPT (0.68) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL11004517 0.82 MAPT (0.46) ALDH1A1MAPTMEN1KMT2ANPC1
Bromide SCHEMBL3048612 0.82 RAB9A (0.94) ALDH1A1MAPTMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111690171-B Flame retardant and flame-retardant PC plastic 广州森赛逖康化工科技有限公司 2022-07-05 CN claimed
CN-112010821-A Recovery method of ethyl aminothiazoly loximate 山东金城医药化工有限公司 2020-12-01 CN claimed
CN-111690171-A Flame retardant and flame-retardant PC plastic 宁波保税区君一汽配科技有限公司 2020-09-22 CN claimed
US-6180238-B1 PARTICULARLY SUITABLE FOR USE IN INK JET PRINTING PROCESSES. XEROX CORPORATION 2001-01-30 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673784-B1 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORP (US) 1999-10-27 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673784-A2 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-4560765-A USING 183-THIAZOL-4-YL GLYOXYLIC ACID AS INTERMEDIATE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-12-24 US claimed
JP-6128231-A None JP disclosed
JP-6345736-A None JP disclosed
US-12331046-B2 CTPS1 inhibitors and uses thereof NIMBUS CLOTHO, INC. (US) 2025-06-17 US disclosed
US-4278793-A ANTIBIOTICS, BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed
US-4278671-A ANTIBIOTICS, BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-07-14 US disclosed
US-4201779-A 7[(2-Amino-thiazol-4-yl)glyoxylamido]-cephem derivatives and processes for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1980-05-06 US disclosed
US-4166115-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331046-B2 CTPS1 inhibitors and uses thereof CTPS1, CTPS2, ECHS1 ALDH1A1 1472/4885MAPT 2064/4885MEN1 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.