Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287615 | 0.84 | CYP19A1 (0.42) | CYP19A1ALOX5APFEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29719546 | 0.83 | KMT2A (0.56) | ALOX5APFEN1ALDH1A1SMN1; SMN2BACE1 | |
| SCHEMBL3287938 | 0.80 | ALDH1A1 (0.62) | CYP19A1FEN1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3287923 | 0.78 | ALOX5AP (0.43) | CYP19A1ALOX5APFEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3293477 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL3591251 | 0.77 | ALDH1A1 (0.44) | CYP19A1ALOX5APFEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7432141 | 0.77 | POLB (0.57) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL169682 | 0.77 | KMT2A (0.55) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL5254828 | 0.74 | CYP11B2 (0.41) | CYP19A1ALOX5APFEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3532363 | 0.74 | ALOX5AP (0.48) | ALOX5APFEN1ALDH1A1SMN1; SMN2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704997-B1 | Amino-tetrazole analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-04-27 | — | — | US | disclosed |
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | ABBVIE INC. | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | P2RX7, P2RX2, P2RX3 | CYP19A1 2491/4885ALOX5AP 1397/4885FEN1 4646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.