Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | UNG | P13051 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863616 | 0.89 | MAOA (0.49) | ALDH1A1TSHRTDP1NPC1RAB9A | |
| SCHEMBL10860684 | 0.87 | RELA (0.46) | ALDH1A1TSHRNPC1RAB9AHPGD | |
| SCHEMBL3870961 | 0.87 | CYP19A1 (0.44) | ALDH1A1TSHRTDP1NPC1RAB9A | |
| SCHEMBL8458900 | 0.87 | NPC1 (0.55) | ALDH1A1TDP1NPC1RAB9ASRC | |
| SCHEMBL9749758 | 0.87 | MAOA (0.48) | ALDH1A1NPC1RAB9AMAOAMAOB | |
| SCHEMBL10990952 | 0.86 | NPC1 (0.50) | ALDH1A1TDP1NPC1RAB9AUNG | |
| Benzaldehyde SCHEMBL432383 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TSHRCYP2A6MAOAMAOB | |
| 3-Nitrobenzaldehyde SCHEMBL7793525 | 0.82 | NFE2L2 (0.54) | ALDH1A1TSHR | |
| SCHEMBL11387681 | 0.81 | NPC1 (0.52) | ALDH1A1TDP1NPC1RAB9ASRC | |
| Isophthalic Dicarboxaldehyde SCHEMBL180566 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TSHRRAB9AUNGSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687545-B2 | N-deacetylthiocolchicine derivatives, their use and pharmaceutical formulations containing them | INDENA S.P.A. (IT) | 2010-03-30 | — | — | US | disclosed |
| US-20080269292-A1 | N-DEACETYLTHIOCOLCHICINE DERIATIVES, THEIR USE AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | INDENA S.P.A. (IT) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269292-A1 | N-DEACETYLTHIOCOLCHICINE DERIATIVES, THEIR USE AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | C9, CCNT2, CCNT1 | ALDH1A1 2076/4885TSHR 2895/4885TDP1 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.