Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894343 | 0.81 | CYP3A4 (0.44) | TSHRPKMALDH1A1NPSR1KMT2A | |
| SCHEMBL1335840 | 0.81 | CES2 (0.52) | TSHRPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL31016401 | 0.81 | CES2 (0.52) | TSHRPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11825925 | 0.80 | PKM (0.39) | TSHRPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9586622 | 0.79 | TSHR (0.61) | TSHRERCC5FEN1PKMALDH1A1 | |
| SCHEMBL14800383 | 0.78 | ALDH1A1 (0.48) | PKMALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL6337922 | 0.77 | TSHR (0.54) | TSHRERCC5FEN1PKMALDH1A1 | |
| SCHEMBL112377 | 0.77 | TSHR (0.65) | TSHRERCC5FEN1PKMALDH1A1 | |
| SCHEMBL29787113 | 0.77 | TSHR (0.65) | TSHRERCC5FEN1PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL23778651 | 0.76 | TSHR (0.52) | TSHRERCC5FEN1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118390125-B | Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof | 深圳市板明科技股份有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118390125-A | Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof | 深圳市板明科技股份有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-118390125-B | Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof | 深圳市板明科技股份有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118390125-A | Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof | 深圳市板明科技股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2018106636-A1 | SHMT INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2018-06-14 | — | — | WO | disclosed |
| EP-2594555-B1 | HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR | ASKA PHARM CO LTD (JP) | 2018-03-07 | — | — | EP | disclosed |
| EP-2594555-A1 | HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR | ASKA Pharmaceutical Co., Ltd. (JP) | 2013-05-22 | — | — | EP | disclosed |
| CN-102985405-A | Heterocyclic compounds and p27Kip1Decomposition inhibitor | ASKA PHARM CO LTD | 2013-03-20 | — | — | CN | disclosed |
| CN-101370796-B | Thiazoles as 11 beta-HSD1 inhibitors | HOFFMANN LA ROCHE | 2012-10-10 | — | — | CN | disclosed |
| US-7645773-B2 | Thiazoles as inhibitors of 11β-hydroxysteroid dehydrogenase | HOFFMANN-LA ROCHE INC. (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645773-B2 | Thiazoles as inhibitors of 11β-hydroxysteroid dehydrogenase | HOFFMANN-LA ROCHE INC. (US) | 2010-01-12 | — | — | US | disclosed |
| EP-1575947-A1 | 2-OXOPYRIDIN-3-YL THIA(DI)AZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES | Amgen Inc. (US) | 2005-09-21 | — | — | EP | disclosed |
| CN-1527822-A | Thiazole derivatives for the treatment of PAAR-related diseases | — | 2004-09-08 | — | — | CN | disclosed |
| WO-2004060890-A1 | 2-OXOPYRIDIN-3-YL THIA (DI) AZOLE DERIVATES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES | AMGEN INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| US-6635434-B1 | Hapten-carrier complex comprising a 1,3-dihalo aromatic compound of given formula; dichlorobenil, chlorthiamid and 2,6-dichlorobenzamide; detection in soil and ground water | EXIQON A/S (DK) | 2003-10-21 | — | — | US | disclosed |
| EP-1204866-A2 | IMMUNOASSAY FOR PESTICIDES AND THEIR DEGRADATION PRODUCTS | Exiqon A/S (DK) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001007912-A3 | IMMUNOASSAY FOR PESTICIDES AND THEIR DEGRADATION PRODUCTS | EXIQON AS (DK) | 2001-12-06 | — | — | WO | disclosed |
| EP-1119557-A1 | INDENO-, NAPHTO- AND BENZOCYCLOHEPTA DIHYDROTHIAZOLE DERIVATIVES, THE PRODUCTION THEREOF AND THEIR USE AS ANORECTIC MEDICAMENTS | Aventis Pharma Deutschland GmbH (DE) | 2001-08-01 | — | — | EP | disclosed |
| WO-2001007912-A2 | IMMUNOASSAY FOR PESTICIDES AND THEIR DEGRADATION PRODUCTS | EXIQON A/S (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2000018749-A1 | INDENO-, NAPHTO- AND BENZOCYCLOHEPTA DIHYDROTHIAZOLE DERIVATIVES, THE PRODUCTION THEREOF AND THEIR USE AS ANORECTIC MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |