SCHEMBL1335840

SCHEMBL1335840

NC(=S)c1ccccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ALDH1A1 P00352 5/20 0.50
PKM P14618 2/20 0.48
POLB P06746 2/20 0.46
MGLL Q99685 1/20 0.46
KDM4E B2RXH2 2/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
HPGD P15428 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31016401 1.00 CES2 (0.52) CES2CES1ALDH1A1PKMPOLB
SCHEMBL5048950 0.82 PKM (0.47) CES2CES1ALDH1A1PKMPOLB
SCHEMBL3537227 0.81 TSHR (0.54) CES2CES1ALDH1A1PKMKDM4E
SCHEMBL609919 0.81 ALDH1A1 (0.42) ALDH1A1PKMPOLBKDM4ETSHR
SCHEMBL11825925 0.79 PKM (0.39) CES2CES1ALDH1A1PKMMGLL
SCHEMBL14800383 0.78 ALDH1A1 (0.48) ALDH1A1PKMPOLBKDM4ELMNA
SCHEMBL31372050 0.77 ALDH1A1 (0.58) CES2CES1ALDH1A1PKMPOLB
SCHEMBL6070107 0.77 CES2 (0.54) CES2CES1ALDH1A1PKMPOLB
SCHEMBL11415841 0.77 ALDH1A1 (0.58) CES2CES1ALDH1A1PKMPOLB
SCHEMBL22843780 0.76 ALDH1A1 (0.52) CES2CES1ALDH1A1PKMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118390125-B Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof 深圳市板明科技股份有限公司 2024-08-16 CN claimed
CN-118390125-A Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof 深圳市板明科技股份有限公司 2024-07-26 CN claimed
EP-0748219-B8 COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS SUGEN INC (US) 2005-06-08 EP claimed
EP-0748219-A4 COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS SUGEN INC (US) 1999-06-16 EP claimed
EP-0748219-A1 COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS Sugen, Inc. (US) 1996-12-18 EP claimed
WO-1995021613-A1 COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS SUGEN, INC. (US) 1995-08-17 WO claimed
CN-118390125-B Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof 深圳市板明科技股份有限公司 2024-08-16 CN disclosed
CN-118390125-B Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof 深圳市板明科技股份有限公司 2024-08-16 CN disclosed
CN-118390125-A Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof 深圳市板明科技股份有限公司 2024-07-26 CN disclosed
CN-118390125-A Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof 深圳市板明科技股份有限公司 2024-07-26 CN disclosed
CN-116969929-A 2- (sulfinyl-5- (2-phenylthiazol-4-yl) -1,3, 4-oxa (thia) diazole compounds, and preparation method and application thereof 长江大学 2023-10-31 CN disclosed
EP-3555198-B1 CURABLE POLYMER LATEX COMPOSITIONS FOR THE MANUFACTURE OF RUBBER ARTICLES SYNTHOMER SDN BHD (MY) 2023-09-20 EP disclosed
US-11230621-B2 Curable polymer latex compositions for the manufacture of rubber articles Synthomer Sdn. Bhd 2022-01-25 US disclosed
US-5192781-A Cardiovascular LABORATOIRES UPSA (FR) 1993-03-09 US disclosed
EP-0368592-A1 Herbicidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-16 EP disclosed
EP-0036711-B1 PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE FBC LIMITED (GB) 1985-12-04 EP disclosed
US-4414221-A MITICIDES, INSECTICIDES, APHIDICIDES FBC LIMITED (GB) 1983-11-08 US disclosed
EP-0036711-A2 Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use FBC LIMITED (GB) 1981-09-30 EP disclosed
US-4197306-A CONTROL OF INSECTS AND ACARIDS UNIROYAL, INC. (US) 1980-04-08 US disclosed
US-4153703-A Method of controlling insects and acarids with certain aryl-substituted thiazoles UNIROYAL, INC. (US) 1979-05-08 US disclosed