Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537227 | 0.80 | TSHR (0.54) | PKMALDH1A1TSHRL3MBTL1KDM4E | |
| SCHEMBL31016401 | 0.79 | CES2 (0.52) | PKMALDH1A1TSHRL3MBTL1KDM4E | |
| SCHEMBL1335840 | 0.79 | CES2 (0.52) | PKMALDH1A1TSHRL3MBTL1KDM4E | |
| SCHEMBL161331 | 0.78 | KDM4E (0.53) | ALDH1A1TSHRKDM4EMAPTLMNA | |
| SCHEMBL30085683 | 0.77 | CD44 (0.41) | PKMALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL14800383 | 0.77 | ALDH1A1 (0.48) | PKMALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL146560 | 0.74 | TSHR (0.63) | ALDH1A1TSHRKDM4EMAPTLMNA | |
| SCHEMBL4096953 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4ELMNACES2 | |
| SCHEMBL11822135 | 0.74 | L3MBTL1 (0.39) | PKMALDH1A1L3MBTL1MAPTCTSL | |
| SCHEMBL71630 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981883-A | Manufacture of 3-amino-2,1-benzisothiazoles | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |