Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC8	Q9BY41	4/20	0.33

▸	KDM4E	B2RXH2	1/20	0.33

▸	NPC1	O15118	1/20	0.33

▸	PABPC1	P11940	1/20	0.33

▸	APOBEC3A	P31941	1/20	0.33

▸	RAB9A	P51151	1/20	0.33

▸	APOBEC3G	Q9HC16	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sulfuric Acid SCHEMBL3540827	0.89	HDAC8 (0.33)	HDAC8KDM4ENPC1PABPC1APOBEC3A
Sulfuric Acid SCHEMBL2866335	0.61	HDAC8 (0.42)	HDAC8KDM4EAPOBEC3AAPOBEC3G
SCHEMBL13415014	0.57	ACHE (0.42)	HDAC8KDM4EPABPC1RAB9A
Sulfuric Acid SCHEMBL1745560	0.57	HDAC8 (0.39)	HDAC8APOBEC3AAPOBEC3G
SCHEMBL31460613	0.56	HDAC8 (0.45)	HDAC8KDM4EAPOBEC3AAPOBEC3G
Benzene SCHEMBL28261045	0.53	CA5A (0.55)	KDM4E
Benzene SCHEMBL27838392	0.53	CA5A (0.55)	KDM4E
Benzene SCHEMBL11808222	0.53	CA5A (0.55)	KDM4E
Benzene SCHEMBL249062	0.52	CA5A (0.67)	KDM4E
Benzene SCHEMBL9118283	0.52	CA5A (0.67)	KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7723522-B2	Pyridine derivative production method	FUJIFILM FINECHEMICALS CO., LTD (JP)	2010-05-25	—	—	US	disclosed
EP-1559711-B1	PREPARATION OF PYRIDINE DERIVATIVES USING PYRIMIDINIUM DERIVATIVES AS INTERMEDIATES	FUJIFILM FINECHEMICALS CO LTD (JP)	2008-06-25	—	—	EP	disclosed
US-20050171355-A1	Pyridine derivative production method	SANKIO CHEMICAL CO., LTD.	2005-08-04	—	—	US	disclosed
EP-1559711-A1	PREPARATION OF PYRIDINE DERIVATIVES USING PYRIMIDINIUM DERIVATIVES AS INTERMEDIATES	Sankio Chemical Co., Ltd. (JP)	2005-08-03	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20050171355-A1	Pyridine derivative production method	CPS1, NAT1, ACMSD	HDAC8 1489/4885KDM4E 779/4885NPC1 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.