Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625722 | 0.75 | MIF (0.60) | MIFALDH1A1BCHEPOLBMAOA | |
| Benzoquinone SCHEMBL7548542 | 0.72 | ALDH1A1 (0.57) | MIFALDH1A1BCHEPOLBMAOA | |
| Benzoquinone SCHEMBL1916998 | 0.72 | ALDH1A1 (0.57) | MIFALDH1A1BCHEPOLBMAOA | |
| SCHEMBL5161488 | 0.70 | MIF (0.54) | MIFALDH1A1BCHEPOLBMAOA | |
| SCHEMBL18483030 | 0.68 | MIF (0.52) | MIFALDH1A1BCHEPOLBMAOA | |
| Benzoquinone SCHEMBL9457254 | 0.67 | TDP1 (0.73) | MIFALDH1A1BCHEPOLBMAOA | |
| SCHEMBL232995 | 0.67 | — | — | |
| Benzoquinone SCHEMBL31324203 | 0.67 | ALDH1A1 (0.89) | MIFALDH1A1BCHEPOLBMAOA | |
| SCHEMBL12330836 | 0.67 | — | — | |
| Benzoquinone SCHEMBL31324224 | 0.67 | ALDH1A1 (0.89) | MIFALDH1A1BCHEPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 989 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695383-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF ACUTE LIVER FAILURE | University of Massachusetts (US) | 2026-02-18 | — | — | EP | claimed |
| US-20250339391-A1 | METHODS FOR EFFECTIVE MANAGEMENT OF PAIN | South Rampart Pharma, Inc. (US) | 2025-11-06 | — | — | US | claimed |
| CN-119061403-A | Aluminum bronze cleaning polishing solution, preparation method and polishing method | 江苏汉宜新材料有限公司 | 2024-12-03 | — | — | CN | claimed |
| US-20240368669-A1 | ACETAMINOPHEN PROTEIN ADDUCTS AND METHODS OF USE THEREOF | BIOVENTURES, LLC | 2024-11-07 | — | — | US | claimed |
| WO-2024216032-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF ACUTE LIVER FAILURE | UNIVERSITY OF MASSACHUSETTS (US) | 2024-10-17 | — | — | WO | claimed |
| CN-117766159-A | Non-steroidal anti-inflammatory drug and liver toxicity risk assessment method of metabolite thereof based on network architecture analysis | 重庆医科大学 | 2024-03-26 | — | — | CN | claimed |
| EP-3672938-B1 | COMPOUNDS FOR AMELIORATING PAIN | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-11-01 | — | — | EP | claimed |
| US-11633371-B2 | Deuterated forms of acetaminophen and uses thereof | Lennham Pharmaceuticals, Inc. (US) | 2023-04-25 | — | — | US | claimed |
| US-20230082397-A1 | ACETAMINOPHEN COMPOUND COMPOSITION WITHOUT SIDE EFFECT TO LIVER | NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION (TW) | 2023-03-16 | — | — | US | claimed |
| US-11534416-B2 | Hepatotoxicity-free pharmaceutical composition containing acetaminophen drugs | NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION (TW) | 2022-12-27 | — | — | US | claimed |
| CN-112294800-A | Application of ellagic acid in preparing medicine for preventing and/or treating nonalcoholic fatty liver disease and liver injury | 四川大学 | 2021-02-02 | — | — | CN | claimed |
| WO-2019200343-A1 | S6K2 BLOCKADE PERTURBS REDOX BALANCE AND FATTY ACID METABOLISM, LEADING TO OXIDATIVE CELL DEATH IN MAPK INHIBITOR RESISTANT CANCERS | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2019-10-17 | — | — | WO | claimed |
| EP-3104849-B1 | ACETAMINOPHEN PROTEIN ADDUCTS AND METHODS OF USE THEREOF | BIOVENTURES LLC (US) | 2019-08-28 | — | — | EP | claimed |
| US-10104882-B2 | Methods and compositions for preventing and treating electrophile-mediated toxicities | MONTEFIORE MEDICAL CENTER (US) | 2018-10-23 | — | — | US | claimed |
| US-20170246194-A1 | Acetaminophen-Containing Analgesic Formulations With Reduced Hepatotoxicity | PURDUE PHARMA L.P. (US) | 2017-08-31 | — | — | US | claimed |
| EP-3104849-A1 | ACETAMINOPHEN PROTEIN ADDUCTS AND METHODS OF USE THEREOF | The Board of Trustees of the University of Arkansas (US) | 2016-12-21 | — | — | EP | claimed |
| WO-2016025897-A1 | ACETAMINOPHEN-CONTAINING ANALGESIC FORMULATIONS WITH REDUCED HEPATOTOXICITY | PURDUE PHARMA L.P. (US) | 2016-02-18 | — | — | WO | claimed |
| WO-2015123574-A1 | ACETAMINOPHEN PROTEIN ADDUCTS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-08-20 | — | — | WO | claimed |
| CN-102149412-A | Hepatoprotectant acetaminophen mutual prodrugs | NEUROGESX INC | 2011-08-10 | — | — | CN | claimed |
| US-5474757-A | Administering diallyl sulfone to prevent metabolism of acetaminophen into hepatotoxic metabolites | RUTGERS UNIVERSITY (US) | 1995-12-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250339391-A1 | METHODS FOR EFFECTIVE MANAGEMENT OF PAIN | SRP72, OPRL1, OPRK1 | MIF 3445/4885ALDH1A1 2342/4885BCHE 2837/4885 |
| US-10104882-B2 | Methods and compositions for preventing and treating electrophile-mediated toxicities | GSTK1, CPT1A, GOT2 | MIF 2068/4885ALDH1A1 125/4885BCHE 1157/4885 |
| US-11633371-B2 | Deuterated forms of acetaminophen and uses thereof | CYP2D6, CYP2E1, HPGD | MIF 2177/4885ALDH1A1 322/4885BCHE 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.