Sugi Predict

Sugi Predict / Compounds / SCHEMBL3544032

SCHEMBL3544032

SCHEMBL3544032

COC(=O)c1ccc(N)c(OC(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.54
▸ KDM4E B2RXH2 7/20 0.54
▸ ALDH1A1 P00352 7/20 0.54
▸ HPGD P15428 5/20 0.54
▸ GAA P10253 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.54
▸ GLA P06280 1/20 0.54
▸ CASP1 P29466 1/20 0.54
▸ CASP7 P55210 1/20 0.54
▸ ATM Q13315 1/20 0.54
▸ EP300 Q09472 2/20 0.51
▸ USP2 O75604 1/20 0.50
▸ BCL2 P10415 1/20 0.47
▸ BCL2L1 Q07817 1/20 0.47
▸ MCL1 Q07820 1/20 0.47
▸ BAK1 Q16611 1/20 0.47
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA7 P43166 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3944216 0.93 CA12 (0.51) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL20764718 0.87 ALDH1A1 (0.60) MAPTALDH1A1HPGDGAAATM
SCHEMBL16369801 0.87 CA12 (0.54) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL1788246 0.87 USP2 (0.61) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL3988566 0.86 MAPT (0.53) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL31685934 0.85 KDM4E (0.49) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL24425908 0.83 MAPT (0.50) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL16369652 0.83 EP300 (0.63) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL2411718 0.83 PARP10 (0.56) EP300BCL2BCL2L1MCL1BAK1
SCHEMBL29010722 0.83 MAPT (0.50) MAPTKDM4EALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002455-A1 NEW N-PHENYLPYRROLAMIDE INHIBITORS OF DNA GYRASE AND TOPOISOMERASE IV WITH ANTIBACTERIAL ACTIVITY UNIV LJUBLJANI (SI) 2025-01-02 — — US disclosed
US-20240382471-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF Hepagene Therapeutics (HK) Limited (CN) 2024-11-21 — — US disclosed
EP-4373821-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF Hepagene Therapeutics (HK) Limited (HK) 2024-05-29 — — EP disclosed
CN-113637017-B Compound containing dihydropterin structure, its preparation method and application 中国药科大学 2024-03-26 — — CN disclosed
CN-117715906-A Glucagon-like peptide-1 receptor modulators and uses thereof 和博医药有限公司 2024-03-15 — — CN disclosed
EP-4263503-A1 NEW N-PHENYLPYRROLAMIDE INHIBITORS OF DNA GYRASE AND TOPOISOMERASE IV WITH ANTIBACTERIAL ACTIVITY Univerza V Ljubljani (SI) 2023-10-25 — — EP disclosed
US-20230125803-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ENANTA PHARM INC (US) 2023-04-27 — — US disclosed
US-20230125803-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ENANTA PHARM INC (US) 2023-04-27 — — US disclosed
WO-2023016134-A1 COMPOUND CONTAINING TETRAHYDROPTERIN STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国药科大学 2023-02-16 — — WO disclosed
US-11572367-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2023-02-07 — — US disclosed
WO-2012166951-A9 NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS RECEPTOS, INC. (US) 2013-02-21 — — WO disclosed
WO-2012166951-A1 NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS RECEPTOS, INC. (US) 2012-12-06 — — WO disclosed
US-7709471-B2 Compounds ASTRAZENECA AB (SE) 2010-05-04 — — US disclosed
EP-2046793-A2 FUSED PYRIMIDO COMPOUNDS AstraZeneca AB (SE) 2009-04-15 — — EP disclosed
WO-2008003958-A2 FUSED PYRIMIDO COMPOUNDS ASTRAZENECA AB (SE) 2008-01-10 — — WO disclosed
US-20080009482-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2008-01-10 — — US disclosed
US-20070123592-A1 Terephthalamide peptidomimetic compounds and methods YALE UNIVERSITY (US) 2007-05-31 — — US disclosed
EP-1723100-A4 TEREPHTHALAMIDE PEPTIDOMIMETIC COMPOUNDS AND METHODS UNIV YALE (US) 2007-04-04 — — EP disclosed
EP-1723100-A2 TEREPHTHALAMIDE PEPTIDOMIMETIC COMPOUNDS AND METHODS YALE UNIVERSITY (US) 2006-11-22 — — EP disclosed
WO-2005079541-A2 TEREPHTHALAMIDE PEPTIDOMIMETIC COMPOUNDS AND METHODS YALE UNIVERSITY (US) 2005-09-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002455-A1 NEW N-PHENYLPYRROLAMIDE INHIBITORS OF DNA GYRASE AND TOPOISOMERASE IV WITH ANTIBACTERIAL ACTIVITY TOP1, TOP2A, TOP2B MAPT 1988/4885KDM4E 963/4885ALDH1A1 2415/4885
US-20070123592-A1 Terephthalamide peptidomimetic compounds and methods CRHBP, ANPEP, DNPEP MAPT 1192/4885KDM4E 4496/4885ALDH1A1 4665/4885
US-20240382471-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF GLP1R, GIPR, GCGR MAPT 4014/4885KDM4E 3593/4885ALDH1A1 2222/4885
US-20080009482-A1 NOVEL COMPOUNDS CYP11B2, CYP11B1, CYP46A1 MAPT 2200/4885KDM4E 3977/4885ALDH1A1 422/4885
US-11572367-B2 Antiviral heterocyclic compounds ACE, HPRT1, ACE2 MAPT 4608/4885KDM4E 1648/4885ALDH1A1 2176/4885
US-20230125803-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ACE, HPRT1, ACE2 MAPT 4608/4885KDM4E 1648/4885ALDH1A1 2176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.