Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.71 |
| ▸ | CDC7 | O00311 | 2/20 | 0.69 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.69 |
| ▸ | PAK4 | O96013 | 1/20 | 0.69 |
| ▸ | PIM1 | P11309 | 1/20 | 0.69 |
| ▸ | CDK2 | P24941 | 1/20 | 0.69 |
| ▸ | FLT3 | P36888 | 1/20 | 0.69 |
| ▸ | GSK3B | P49841 | 1/20 | 0.69 |
| ▸ | CDK9 | P50750 | 1/20 | 0.69 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.69 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.69 |
| ▸ | MELK | Q14680 | 1/20 | 0.69 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.69 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.69 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.69 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.69 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294594 | 1.00 | FABP4 (0.71) | FABP4CDC7DAPK3PAK4PIM1 | |
| SCHEMBL22453647 | 0.94 | FABP4 (0.63) | FABP4CDC7DAPK3PAK4PIM1 | |
| SCHEMBL18109767 | 0.91 | FABP4 (0.85) | FABP4CDC7DAPK3PAK4PIM1 | |
| SCHEMBL7841736 | 0.87 | FABP4 (0.85) | FABP4PTGS1AKR1C3AKR1C2MAPK8 | |
| Fenamic Acid SCHEMBL29622832 | 0.87 | FABP4 (0.92) | FABP4PTGS1AKR1C3AKR1C2MAPK8 | |
| Fenamic Acid SCHEMBL25828 | 0.87 | FABP4 (0.92) | FABP4PTGS1AKR1C3AKR1C2MAPK8 | |
| Fenamic Acid SCHEMBL11800213 | 0.85 | FABP4 (0.89) | FABP4PTGS1AKR1C3AKR1C2MAPK8 | |
| Fenamic Acid SCHEMBL3657701 | 0.85 | FABP4 (0.89) | FABP4PTGS1AKR1C3AKR1C2MAPK8 | |
| Fenamic Acid SCHEMBL28520019 | 0.85 | FABP4 (0.89) | FABP4PTGS1AKR1C3AKR1C2MAPK8 | |
| Fenamic Acid SCHEMBL10800939 | 0.85 | FABP4 (0.89) | FABP4PTGS1AKR1C3AKR1C2MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813938-A | Conjugated small molecule modified hydrogel and preparation method thereof | 金陵科技学院 | 2023-09-29 | — | — | CN | disclosed |
| CN-113683615-A | Evodiamine derivative and preparation and application thereof | 南华大学 | 2021-11-23 | — | — | CN | disclosed |
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |
| CN-110229114-A | Remove C2-symmetric diphenylamine type chiral bisoxazoline ligand and synthetic method and application thereof | 浙江工业大学 | 2019-09-13 | — | — | CN | disclosed |
| US-9126935-B2 | Aurora kinase modulators and methods of use | AMGEN INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-9126935-B2 | Aurora kinase modulators and methods of use | AMGEN INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-9126935-B2 | Aurora kinase modulators and methods of use | AMGEN INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20120015373-A1 | ACRIDONE DERIVATIVES AS LABELS FOR FLUORESCENCE DETECTION OF TARGET MATERIALS | GE HEALTHCARE UK LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20110294837-A1 | Aurora Kinase Modulators and Methods of Use | AMGEN INC. | 2011-12-01 | — | — | US | disclosed |
| US-20110294837-A1 | Aurora Kinase Modulators and Methods of Use | AMGEN INC. | 2011-12-01 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-05-21 | — | — | US | disclosed |
| US-20080139788-A1 | ACRIDONE DERIVATIVES AS LABELS FOR FLUORESCENCE DETECTION OF TARGET MATERIALS | GE HEALTHCARE UK LIMITED (GB) | 2008-06-12 | — | — | US | disclosed |
| US-20070031854-A1 | Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses | KATSILOMETES GEORGE W | 2007-02-08 | — | — | US | disclosed |
| US-20040191792-A1 | Acridone derivatives as labels for fluorescence detection of target materials | GE HEALTHCARE UK LIMITED (GB) | 2004-09-30 | — | — | US | disclosed |
| EP-1392776-A2 | ACRIDONE DERIVATIVES AS LABELS FOR FLUORESCENCE DETECTION OF TARGET MATERIALS | Amersham Biosciences UK Limited (GB) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002099424-A2 | ACRIDONE DERIVATIVES AS LABELS FOR FLUORESCENCE DETECTION OF TARGET MATERIALS | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2002-12-12 | — | — | WO | disclosed |
| US-20020034828-A1 | NOVEL 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND THEIR PREPARATION | PIERCE CHEMICAL COMPANY | 2002-03-21 | — | — | US | disclosed |
| EP-1026156-A2 | Novel 10, 10'-substituted-9,9'-biacridine luminescent molecules and their preparation | PIERCE CHEMICAL COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | CLIC1, ASIC1, CLIC4 | FABP4 1600/4885CDC7 2731/4885DAPK3 2212/4885 |
| US-20110294837-A1 | Aurora Kinase Modulators and Methods of Use | AURKC, AURKA, CDK1 | FABP4 4681/4885CDC7 16/4885DAPK3 582/4885 |
| US-20080139788-A1 | ACRIDONE DERIVATIVES AS LABELS FOR FLUORESCENCE DETECTION OF TARGET MATERIALS | ACR, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ARSA | FABP4 1977/4885CDC7 3359/4885DAPK3 1543/4885 |
| US-20040191792-A1 | Acridone derivatives as labels for fluorescence detection of target materials | ACR, ARSA, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | FABP4 1027/4885CDC7 3981/4885DAPK3 2048/4885 |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | FABP4 3844/4885CDC7 4594/4885DAPK3 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.