Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265924 | 0.79 | ALDH1A1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL8599162 | 0.74 | — | — | |
| SCHEMBL14559286 | 0.74 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL25367235 | 0.74 | — | — | |
| SCHEMBL19686201 | 0.73 | — | — | |
| SCHEMBL5500429 | 0.73 | CA2 (0.36) | TSHRALDH1A1 | |
| SCHEMBL21775705 | 0.73 | CA2 (0.36) | TSHRALDH1A1 | |
| SCHEMBL26663588 | 0.73 | HDAC6 (0.34) | — | |
| Acetone SCHEMBL8319174 | 0.73 | LMNA (0.46) | TSHRALDH1A1 | |
| SCHEMBL6168840 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | TSHR 2748/4885ALDH1A1 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.