Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTTP | P55157 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3541193 | 0.91 | LSS (0.45) | TMEM97SIGMAR1LSSMEN1KMT2A | |
| SCHEMBL3544748 | 0.81 | SLC6A5 (0.37) | TMEM97SIGMAR1KMT2AALDH1A1HDAC4 | |
| SCHEMBL3540714 | 0.75 | MEN1 (0.43) | LSSMAPK14MEN1KMT2AEPHX2 | |
| SCHEMBL12334073 | 0.73 | CCKBR (0.49) | MAPK14MEN1KMT2AEPHX2PPARA | |
| SCHEMBL3542265 | 0.72 | TMEM97 (0.53) | TMEM97SIGMAR1LSSKMT2AALDH1A1 | |
| SCHEMBL6753597 | 0.70 | CCR2 (0.52) | MAPK14MEN1KMT2AMAOA | |
| SCHEMBL2634030 | 0.70 | MAPK14 (0.76) | LSSMAPK14HDAC3HDAC6EPHX2 | |
| SCHEMBL13881587 | 0.69 | MEN1 (0.54) | MEN1KMT2AHDAC3ALDH1A1HDAC6 | |
| SCHEMBL14055925 | 0.69 | LSS (0.52) | TMEM97SIGMAR1LSSMAPK14MEN1 | |
| SCHEMBL3543299 | 0.68 | MEN1 (0.46) | LSSMAPK14MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683078-B2 | Arylsulfonamide derivatives as C-Jun-N-Terminal Kinases (JNK's) inhibitors | LABORATOIRES SERONO S.A. (CH) | 2010-03-23 | — | — | US | claimed |