Sugi Predict

Sugi Predict / Compounds / SCHEMBL3545400

SCHEMBL3545400

SCHEMBL3545400

COC(=O)c1cc(S)cc(S)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 4/20 0.58
▸ CA2 P00918 4/20 0.58
▸ CA12 O43570 3/20 0.58
▸ CA7 P43166 3/20 0.58
▸ CA9 Q16790 3/20 0.58
▸ CA14 Q9ULX7 3/20 0.58
▸ KDM4E B2RXH2 5/20 0.56
▸ XDH P47989 2/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ GAA P10253 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ POLB P06746 2/20 0.56
▸ NFKB1 P19838 1/20 0.56
▸ GFER P55789 1/20 0.56
▸ NFKB2 Q00653 1/20 0.56
▸ RELA Q04206 1/20 0.56
▸ FUT7 Q11130 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ ALDH1A1 P00352 3/20 0.52
▸ TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3148712 0.95 CA1 (0.58) CA1CA2CA12CA7CA9
SCHEMBL23699475 0.87 KDM4E (0.50) CA1CA2CA12CA7CA9
SCHEMBL3550884 0.86 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL21031070 0.86 ALDH1A1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL24071359 0.86 NOTUM (0.57) CA1CA2CA12CA7CA9
SCHEMBL31401176 0.86 ALDH1A1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL147169 0.82 CA1 (0.71) CA1CA2CA12CA7CA9
SCHEMBL12166938 0.81 NOTUM (0.66) CA1CA2CA12CA7CA9
SCHEMBL190224 0.79 TSHR (0.57) CA1CA2CA12CA7CA9
SCHEMBL19186006 0.78 CA1 (0.60) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7205428-B2 Thioether derivatives, their method for production and use NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) 2007-04-17 — — US claimed
US-12612386-B2 Heteroaryl-triazole compounds as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2026-04-28 — — US disclosed
CN-115996639-B Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2025-06-13 — — CN disclosed
EP-4146643-B1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AG (DE) 2024-05-29 — — EP disclosed
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 — — US disclosed
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 — — US disclosed
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 — — US disclosed
CN-115996639-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2023-04-21 — — CN disclosed
EP-4146643-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2023-03-15 — — EP disclosed
WO-2021224323-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-11-11 — — WO disclosed
US-20080058304-A1 N-hydroxyamide derivatives possessing antibacterial activity VICURON HOLDINGS LLC 2008-03-06 — — US disclosed
EP-1539744-A4 N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARM INC (US) 2007-06-06 — — EP disclosed
US-7205428-B2 Thioether derivatives, their method for production and use NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) 2007-04-17 — — US disclosed
EP-1539744-A2 N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY Vicuron Pharmaceuticals, Inc. (US) 2005-06-15 — — EP disclosed
EP-1219667-B1 Novel thioether derivatives, their method for production and use COMM RES LAB INDEPENDENT ADMIN (JP) 2004-08-04 — — EP disclosed
WO-2004007444-A2 N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS, INC. (US) 2004-01-22 — — WO disclosed
US-6630578-B2 Which respond immediately by emission of light when stimulated with light or electric energy, and are useful as switching material of memory COMMUNICATIONS RESEARCH LABORATORY, INDEPENDENT ADMINISTRATIVE INSTITUTION (JP) 2003-10-07 — — US disclosed
US-20030171507-A1 Novel thioether derivatives, their method for production and use NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) 2003-09-11 — — US disclosed
EP-1219667-A2 Novel thioether derivatives, their method for production and use Communications Research Laboratory, Independent Administrative Institution (JP) 2002-07-03 — — EP disclosed
US-20020072583-A1 Novel thioether derivatives, their method for production and use NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) 2002-06-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES CYP4F3, CYP4X1, GLRX3 CA1 4440/4885CA2 3769/4885CA12 4860/4885
US-12612386-B2 Heteroaryl-triazole compounds as pesticides CBR3, CYCS, HCN1 CA1 823/4885CA2 552/4885CA12 3431/4885
US-20080058304-A1 N-hydroxyamide derivatives possessing antibacterial activity AMDHD2, OGA, ENGASE CA1 4363/4885CA2 4383/4885CA12 3880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.