SCHEMBL3148712

SCHEMBL3148712

COC(=O)c1cc(S)cc(C(=O)OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA12 O43570 3/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
KDM4E B2RXH2 5/20 0.56
XDH P47989 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
LMNA P02545 2/20 0.56
POLB P06746 2/20 0.56
GAA P10253 1/20 0.56
NFKB1 P19838 1/20 0.56
GFER P55789 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
FUT7 Q11130 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 3/20 0.52
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3545400 0.95 CA1 (0.58) CA1CA2CA12CA7CA9
SCHEMBL23699475 0.92 KDM4E (0.50) CA1CA2CA12CA7CA9
SCHEMBL147169 0.87 CA1 (0.71) CA1CA2CA12CA7CA9
SCHEMBL3550884 0.86 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL21031070 0.86 ALDH1A1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL24071359 0.86 NOTUM (0.57) CA1CA2CA12CA7CA9
SCHEMBL31401176 0.86 ALDH1A1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL12166938 0.81 NOTUM (0.66) CA1CA2CA12CA7CA9
SCHEMBL1949259 0.80 CA1 (0.62) CA1CA2CA12CA7CA9
SCHEMBL190224 0.79 TSHR (0.57) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8728688-B2 Colored curable composition, color filter and method of producing the same, and dipyrromethene metal complex compound and tautomer thereof FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8343696-B2 Colored curable composition, fluorine-containing dipyrromethene compound and tautomer thereof, and fluorine-containing dipyrromethene metal complex and tautomer thereof, and color filter using the same and method for producing the color filter FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-8343696-B2 Colored curable composition, fluorine-containing dipyrromethene compound and tautomer thereof, and fluorine-containing dipyrromethene metal complex and tautomer thereof, and color filter using the same and method for producing the color filter FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-8334085-B2 Colored curable composition, color filter and method of producing the same, and dipyrromethene metal complex compound and tautomer thereof FUJIFILM CORPORATION (JP) 2012-12-18 US disclosed
US-20120315579-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2012-12-13 US disclosed
US-7820357-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2010-10-26 US disclosed
US-20100081071-A1 COLORED CURABLE COMPOSITION, FLUORINE-CONTAINING DIPYRROMETHENE COMPOUND AND TAUTOMER THEREOF, AND FLUORINE-CONTAINING DIPYRROMETHENE METAL COMPLEX AND TAUTOMER THEREOF, AND COLOR FILTER USING THE SAME AND METHOD FOR PRODUCING THE COLOR FILTER FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100081071-A1 COLORED CURABLE COMPOSITION, FLUORINE-CONTAINING DIPYRROMETHENE COMPOUND AND TAUTOMER THEREOF, AND FLUORINE-CONTAINING DIPYRROMETHENE METAL COMPLEX AND TAUTOMER THEREOF, AND COLOR FILTER USING THE SAME AND METHOD FOR PRODUCING THE COLOR FILTER FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100055582-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
EP-0502723-A2 Water-soluble tetraazaporphins and fluorochrome for labeling HITACHI CHEMICAL CO., LTD. (JP) 1992-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055582-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF MAPT, UACA, HELZ CA1 390/4885CA2 1560/4885CA12 183/4885
US-20100081071-A1 COLORED CURABLE COMPOSITION, FLUORINE-CONTAINING DIPYRROMETHENE COMPOUND AND TAUTOMER THEREOF, AND FLUORINE-CONTAINING DIPYRROMETHENE METAL COMPLEX AND TAUTOMER THEREOF, AND COLOR FILTER USING THE SAME AND METHOD FOR PRODUCING THE COLOR FILTER SCO2, TDO2, FTH1 CA1 681/4885CA2 1227/4885CA12 886/4885
US-20120315579-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF MAPT, UACA, HELZ CA1 390/4885CA2 1560/4885CA12 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.