Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358184 | 0.71 | S100A4 (0.59) | S100A4CDC25BALDH1A1IDO1MAOA | |
| SCHEMBL28289103 | 0.71 | S100A4 (0.59) | S100A4CDC25BALDH1A1IDO1MAOA | |
| SCHEMBL2599222 | 0.71 | S100A4 (1.00) | S100A4CCR1CDC25BALDH1A1IDO1 | |
| SCHEMBL3657123 | 0.70 | HDAC6 (0.50) | S100A4ALDH1A1MAOBLMNAHPGD | |
| SCHEMBL3657118 | 0.70 | HDAC6 (0.50) | S100A4ALDH1A1MAOBLMNAHPGD | |
| SCHEMBL6412872 | 0.67 | S100A4 (0.58) | S100A4CDC25BALDH1A1IDO1MAOA | |
| SCHEMBL2830315 | 0.67 | CCR1 (0.42) | CCR1ALDH1A1MEN1LMNAHPGD | |
| SCHEMBL9301644 | 0.65 | S100A4 (0.48) | S100A4CCR1MAOBCYP1A2MAPK1 | |
| SCHEMBL6375662 | 0.62 | PADI1 (0.62) | S100A4CCR1CDC25BALDH1A1IDO1 | |
| SCHEMBL5800358 | 0.62 | MAPT (0.53) | S100A4CDC25BALDH1A1IDO1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807668-B2 | Anti-inflammatory compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2010-10-05 | — | — | US | disclosed |
| US-20070265253-A1 | Anti-Inflammatory Compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-11-15 | — | — | US | disclosed |
| EP-1789422-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006031134-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265253-A1 | Anti-Inflammatory Compounds | TNF, PTGS1, PTGES | S100A4 64/4885CCR1 238/4885CDC25B 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.