SCHEMBL3549805

SCHEMBL3549805

COC(=O)CO/N=C(\C(=O)O)C(=O)CCl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3549809 1.00 TSHR (0.31) TSHRLMNA
SCHEMBL6133165 1.00 TSHR (0.31) TSHRLMNA
SCHEMBL28455957 0.83 TSHR (0.31) TSHR
SCHEMBL12374922 0.82
SCHEMBL5880313 0.81 TSHR (0.32) TSHR
SCHEMBL3767455 0.81 TSHR (0.32) TSHR
SCHEMBL3767458 0.81 TSHR (0.32) TSHR
SCHEMBL9482960 0.80 MGAM (0.37) TSHR
SCHEMBL28439843 0.80 MGAM (0.37) TSHR
SCHEMBL9482958 0.80 MGAM (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430526-B Cefixime side chain ring opening acid impurity and preparation method thereof 山东金城柯瑞化学有限公司 2024-04-02 CN disclosed
CN-117510367-B Preparation method of cefixime side chain open-loop acid 山东金城柯瑞化学有限公司 2024-03-12 CN disclosed
CN-117510367-A Preparation method of cefixime side chain open-loop acid 山东金城柯瑞化学有限公司 2024-02-06 CN disclosed
CN-117430526-A Cefixime side chain ring opening acid impurity and preparation method thereof 山东金城柯瑞化学有限公司 2024-01-23 CN disclosed
US-7705142-B2 Process for the preparation of cefixime HETERO DRUGS LIMITED (IN) 2010-04-27 US disclosed
EP-1863822-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME HETERO DRUGS LTD (IN) 2009-10-14 EP disclosed
US-20080242858-A1 Process For the Preparation of Cefixime HETERO DRUGS LIMITED (IN) 2008-10-02 US disclosed
EP-1863822-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME Hetero Drugs Limited (IN) 2007-12-12 EP disclosed
WO-2006103686-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME HETERO DRUGS LIMITED (IN) 2006-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242858-A1 Process For the Preparation of Cefixime ACMSD, HAAO, HDHD5 TSHR 4367/4885LMNA 4102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.