Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12270233 | 0.87 | TOP1 (0.41) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1800270 | 0.85 | HSD17B10 (0.41) | ALDH1A1HSD17B10KDM4EHPGDNPC1 | |
| SCHEMBL12270203 | 0.76 | TOP1 (0.41) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1681771 | 0.76 | PTGS2 (0.65) | PTGS2BCAT2PTGS1 | |
| Ammonia Solution, Strong SCHEMBL28994523 | 0.74 | PTGS2 (0.62) | PTGS2BCAT2PTGS1 | |
| Hydrogen Sulfide SCHEMBL27804205 | 0.74 | PTGS2 (0.62) | PTGS2BCAT2PTGS1 | |
| SCHEMBL2782853 | 0.74 | PTGS2 (0.68) | PTGS2BCAT2PTGS1 | |
| SCHEMBL7737501 | 0.72 | PTGS2 (0.66) | PTGS2BCAT2PTGS1 | |
| SCHEMBL12270289 | 0.72 | PTGS2 (0.56) | PTGS2BCAT2PTGS1 | |
| SCHEMBL2133316 | 0.72 | PTGS2 (0.66) | PTGS2BCAT2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834216-B2 | Desmosdumotins, the method for preparing the same and use as anti-tumor or anti-AIDS agents | Wu, Jiuhong (CN) | 2010-11-16 | — | — | US | claimed |
| US-20090233998-A1 | Desmosdumotins, the Method for Preparing the Same and Use as Anti-Tumor or Anti-AIDS Agents | WU, JIUHONG (CN) | 2009-09-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233998-A1 | Desmosdumotins, the Method for Preparing the Same and Use as Anti-Tumor or Anti-AIDS Agents | DSG1, DSC1, SOST | PTGS2 3607/4885SMARCA2 240/4885PBRM1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.