Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 6/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540607 | 0.82 | S100A4 (0.52) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL3554537 | 0.71 | TDP2 (0.45) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL5915065 | 0.71 | TDP2 (0.81) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL29746876 | 0.69 | GAA (0.78) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL1103717 | 0.69 | GAA (0.78) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL5915061 | 0.69 | GAA (0.86) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL7710160 | 0.68 | TDP2 (0.47) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL9267635 | 0.67 | TDP2 (0.74) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL460433 | 0.67 | TDP2 (1.00) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL29551149 | 0.67 | GAA (1.00) | PTPRCCTSLCTSSPTPN13TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807668-B2 | Anti-inflammatory compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2010-10-05 | — | — | US | disclosed |
| US-20070265253-A1 | Anti-Inflammatory Compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-11-15 | — | — | US | disclosed |
| EP-1789422-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006031134-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265253-A1 | Anti-Inflammatory Compounds | TNF, PTGS1, PTGES | PTPRC 3605/4885CTSL 697/4885CTSS 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.