SCHEMBL3551620

SCHEMBL3551620

CCOc1cccc(O)c1C=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAPT P10636 3/20 0.44
GAA P10253 3/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GLA P06280 1/20 0.43
LMNA P02545 3/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
JAK2 O60674 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4180647 0.87 LMNA (0.48) ALDH1A1MAPTGAAL3MBTL1NPSR1
SCHEMBL15357251 0.85 GAA (0.56) ALDH1A1CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL24135768 0.84 GAA (0.43) ALDH1A1CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL19442903 0.84 ALDH1A1 (0.57) ALDH1A1GAAL3MBTL1LMNAMEN1
SCHEMBL11382179 0.83 GAA (0.51) ALDH1A1CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL10922927 0.83 BACE1 (0.52) ALDH1A1CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL15349839 0.83 LMNA (0.47) ALDH1A1CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL24080812 0.82 GAA (0.50) ALDH1A1CYP3A4MAPTGAAL3MBTL1
SCHEMBL28266853 0.81 GAA (0.48) ALDH1A1CYP1A2CYP3A4CYP2C8CYP2C9
SCHEMBL13812603 0.80 ALDH1A1 (0.43) ALDH1A1MAPTGAAL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974828-B Compounds as protein phosphatase 5 agonists, methods of preparation and uses thereof 中国药科大学 2025-02-11 CN disclosed
CN-115974828-A Compound as protein phosphatase 5 agonist and preparation method and application thereof 中国药科大学 2023-04-18 CN disclosed
CN-109535185-A One kind is using 4-(4- methyl piperidine) -3- thiosemicarbazones is the gold complex of ligand and its synthetic method and application 广西师范大学 2019-03-29 CN disclosed
US-9375434-B2 Antitumor effect potentiator composed of imidazooxazine compound TAIHO PHARMACEUTICAL CO., LTD. (JP) 2016-06-28 US disclosed
US-9375434-B2 Antitumor effect potentiator composed of imidazooxazine compound TAIHO PHARMACEUTICAL CO., LTD. (JP) 2016-06-28 US disclosed
US-9289431-B2 2016-03-22 US disclosed
US-9289431-B2 2016-03-22 US disclosed
EP-2698372-B1 NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2016-02-03 EP disclosed
US-9187510-B2 Light-emitting organic platinum complex, light-emitting material containing this complex and functional device OSAKA UNIVERSITY (JP) 2015-11-17 US disclosed
US-20150164909-A1 ANTITUMOR EFFECT POTENTIATOR COMPOSED OF IMIDAZOOXAZINE COMPOUND TAIHO PHARMACEUTICAL CO., LTD. (JP) 2015-06-18 US disclosed
US-8772283-B2 Imidazo-oxazine compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2014-07-08 US disclosed
EP-2698372-A1 NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2014-02-19 EP disclosed
WO-2014007217-A1 ANTITUMOR EFFECT POTENTIATOR COMPOSED OF IMIDAZOOXAZINE COMPOUND 大鵬薬品工業株式会社 (JP) 2014-01-09 WO disclosed
US-20130001535-A1 LIGHT-EMITTING ORGANIC PLATINUM COMPLEX, LIGHT-EMITTING MATERIAL CONTAINING THIS COMPLEX AND FUNCTIONAL DEVICE OSAKA UNIVERSITY (JP) 2013-01-03 US disclosed
WO-2012137870-A1 NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF 大鵬薬品工業株式会社 (JP) 2012-10-11 WO disclosed
US-7745229-B2 Chemoselective fluorgenic molecular linkers and methods for their preparation and use UNIVERSITY OF SOUTH CAROLINA 2010-06-29 US disclosed
US-20070224695-A1 Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use UNIVERSITY OF SOUTH CAROLINA (US) 2007-09-27 US disclosed
WO-2005103705-A2 CHEMOSELECTIVE FLUOROGENIC MOLECULAR LINKERS AND METHODS OF THEIR PREPARATION AND USE UNIVERSITY OF SOUTH CAROLINA (US) 2005-11-03 WO disclosed
US-4399148-A SYSTEMIC PESTICIDES; APHIDICIDES UNION CARBIDE CORPORATION (US) 1983-08-16 US disclosed
EP-0067503-A1 Hydroxyaryliminoaryl carbamates, imine bisphenols and derivatives thereof useful as insecticidal compositions UNION CARBIDE CORPORATION (US) 1982-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150164909-A1 ANTITUMOR EFFECT POTENTIATOR COMPOSED OF IMIDAZOOXAZINE COMPOUND H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, TPD52L2 ALDH1A1 955/4885CYP1A2 1022/4885CYP3A4 1675/4885
US-20070224695-A1 Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use KIT, HLCS, ALK ALDH1A1 1386/4885CYP1A2 4438/4885CYP3A4 3293/4885
US-20130001535-A1 LIGHT-EMITTING ORGANIC PLATINUM COMPLEX, LIGHT-EMITTING MATERIAL CONTAINING THIS COMPLEX AND FUNCTIONAL DEVICE CRY2, C9, PMS2 ALDH1A1 1500/4885CYP1A2 440/4885CYP3A4 2105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.