SCHEMBL3552508

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8201115	0.83	KDM4E (0.47)	NPC1RAB9AMEN1KMT2ASMN1; SMN2
	SCHEMBL12283568	0.80	SMN1; SMN2 (0.39)	NPC1RAB9AMEN1KMT2ASMN1; SMN2
	SCHEMBL3550205	0.78	AMPD3 (0.40)	NPC1RAB9AMEN1KMT2AAMPD3
	SCHEMBL14286158	0.78	ACHE (0.36)	NPC1RAB9AMEN1KMT2ANLRP3
	SCHEMBL18584530	0.78	ACHE (0.43)	KDM4EHSD17B10
	SCHEMBL3553700	0.77	CA12 (0.50)	NPC1RAB9AMEN1KMT2AAMPD3
	SCHEMBL16616336	0.75	DRD2 (0.40)	NPC1RAB9ASMN1; SMN2CA12CA1
	SCHEMBL17787366	0.75	DRD2 (0.40)	NPC1RAB9AMEN1KMT2ASMN1; SMN2
	SCHEMBL3000425	0.74	NLRP3 (0.43)	NPC1RAB9AMEN1KMT2ANLRP3
	SCHEMBL2865009	0.74	CA12 (0.51)	NPC1RAB9AMEN1KMT2AAMPD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.