Water

Water

SCHEMBL355268

O.O.O.O.O.O.O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Nd+3]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
CA5A P35218 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL719743 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL7147199 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28135661 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL21433567 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL9655758 0.94 MEN1 (0.60) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL9655753 0.94 MEN1 (0.60) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10566608 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL2590832 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
SCHEMBL194086 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28398822 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 789 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122039430-A Multi-dimensional optically tunable flexible material and preparation method thereof 武汉纺织大学 2026-05-15 CN claimed
CN-121812656-B Method for improving interface binding force and electrical performance of cathode side of solid oxide fuel cell 常州翌晶氢能科技有限公司 2026-05-15 CN claimed
CN-119263467-B Preparation method of self-purification stepped ring packing 沈阳理工大学 2026-05-15 CN claimed
EP-4630187-A1 PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT Bahçesehir Üniversitesi (TR) 2025-10-15 EP claimed
US-12391977-B2 Mixed cluster heterometallic metal-organic frameworks for complex optical tags NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2025-08-19 US claimed
CN-120191970-A Neodymium-zirconium co-substituted M-type strontium ferrite wave-absorbing material and preparation method thereof 合肥工业大学 2025-06-24 CN claimed
CN-120082780-A Flame-retardant light alloy for aviation and preparation process thereof 江苏中福铝镁科技有限公司 2025-06-03 CN claimed
CN-119798288-A Dielectric constant switchable NIR (near infrared) luminescent nitrate radical bridged bimetallic phase change material as well as preparation method and application thereof 江西理工大学 2025-04-11 CN claimed
CN-119330407-B Carbon dioxide gas-sensitive material based on platinum-modified neodymium iron magnesium oxide, and preparation method and application thereof 山东建筑大学 2025-03-21 CN claimed
CN-119601693-A Rare earth doped Pt-based high-entropy intermetallic compound, preparation and application 吉林大学 2025-03-11 CN claimed
CN-109957251-A A kind of preparation method of rubber compound 江西双龙硅材料科技有限公司 2019-07-02 CN claimed
US-20180130579-A1 MAGNETIC MATERIAL AND A METHOD OF SYNTHESISING THE SAME ROLLS-ROYCE PLC (GB) 2018-05-10 US claimed
EP-3319093-A1 A MAGNETIC MATERIAL AND A METHOD OF SYNTHESISING THE SAME Rolls-Royce plc (GB) 2018-05-09 EP claimed
US-9647275-B2 Bi-functional catalysts for oxygen reduction and oxygen evolution STC.UNM (US) 2017-05-09 US claimed
US-20150180046-A1 Bi-Functional Catalysts for Oxygen Reduction and Oxygen Evolution STC.UNM (US) 2015-06-25 US claimed
US-8765028-B2 Composition for oxide thin film, method of preparing the composition, method of forming the oxide thin film, and electronic device using the composition INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2014-07-01 US claimed
US-8759247-B2 Methanol electro-oxidation catalyst and method of making the same KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2014-06-24 US claimed
WO-2013187976-A1 BI-FUNCTIONAL CATALYSTS FOR OXYGEN REDUCTION AND OXYGEN EVOLUTION STC.UNM (US) 2013-12-19 WO claimed
US-20130165318-A1 METHANOL ELECTRO-OXIDATION CATALYST AND METHOD OF MAKING THE SAME KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2013-06-27 US claimed
US-20120049181-A1 COMPOSITION FOR OXIDE THIN FILM, METHOD OF PREPARING THE COMPOSITION, METHOD OF FORMING THE OXIDE THIN FILM, AND ELECTRONIC DEVICE USING THE COMPOSITION INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2012-03-01 US claimed