SCHEMBL3553798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3557320	0.96	HTR6 (0.44)	HTR6PSEN1PSEN2APH1BNCSTN
	SCHEMBL3562472	0.92	HTR6 (0.42)	HTR6PSEN1PSEN2APH1BNCSTN
	SCHEMBL3557150	0.92	HTR6 (0.48)	HTR6PTGDRPTGDR2
	SCHEMBL3563804	0.92	HTR6 (0.48)	HTR6PSEN1PSEN2APH1BNCSTN
	SCHEMBL3928794	0.92	HTR6 (0.50)	HTR6PSEN1PSEN2APH1BNCSTN
	SCHEMBL3935775	0.91	PSEN1 (0.41)	HTR6PSEN1PSEN2APH1BNCSTN
	SCHEMBL3563475	0.87	HTR6 (0.47)	HTR6PSEN1PSEN2APH1BNCSTN
	SCHEMBL3555658	0.86	AGTR1 (0.44)	HTR6PSEN1PSEN2APH1BNCSTN
	SCHEMBL3560635	0.85	CYP1A2 (0.37)	HTR6LMNAKDM4EALDH1A1HTT
	SCHEMBL3561790	0.85	HTR6 (0.51)	HTR6PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.