Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1047653 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL9150491 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7145282 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10904945 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10896609 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10566608 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL193086 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122016961-A | Modified electrode for detecting perfluorooctane sulfonate in electrogalvanizing solution and preparation method thereof | 常州大学 | 2026-05-12 | — | — | CN | claimed |
| CN-121571173-A | Fluorine doped high entropy oxide catalyst and preparation method and application thereof | 河北工业大学 | 2026-02-27 | — | — | CN | claimed |
| EP-4630187-A1 | PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT | Bahçesehir Üniversitesi (TR) | 2025-10-15 | — | — | EP | claimed |
| US-20250312777-A1 | CUBIC FLUORITE RARE-EARTH HIGH ENTROPY OXIDES AND THEIR CATALYSIS APPLICATIONS | UNIV KHALIFA SCIENCE & TECHNOLOGY (AE) | 2025-10-09 | — | — | US | claimed |
| CN-116809070-B | Monoatomic catalyst for low-temperature reverse steam transformation and preparation method thereof | 燕山大学 | 2025-05-13 | — | — | CN | claimed |
| CN-119852431-A | Double-layer perovskite cathode material and preparation method and application thereof | 浙江理工大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119733500-A | Low-temperature rare earth-based denitration catalyst with nano synaptic structure and preparation method and application thereof | 南京工业大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119638550-A | Green methanol preparation method of controllable micro-channel reactor based on low-temperature plasma activation | 武汉京运新能源云技术有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119591165-A | Spin regulation method of perovskite oxide and application of perovskite oxide in electrocatalytic nitrate reduction reaction | 江南大学 | 2025-03-11 | — | — | CN | claimed |
| CN-119601693-A | Rare earth doped Pt-based high-entropy intermetallic compound, preparation and application | 吉林大学 | 2025-03-11 | — | — | CN | claimed |
| CN-110845523-A | Rare earth metal organic complex microsphere wave-absorbing material and preparation method thereof | 中国海洋大学 | 2020-02-28 | — | — | CN | claimed |
| CN-110615807-A | Rare earth metal organic complex wave-absorbing material and preparation method thereof | 中国海洋大学 | 2019-12-27 | — | — | CN | claimed |
| CN-110560074-A | Preparation method and application of Pr modified Co-B catalyst | 天津工业大学 | 2019-12-13 | — | — | CN | claimed |
| CN-109453761-A | A kind of SCR honeycomb type denitrating catalyst and preparation method thereof | 华电青岛环保技术有限公司 | 2019-03-12 | — | — | CN | claimed |
| CN-108404902-A | A kind of SCR honeycomb types denitrating catalyst and preparation method thereof | 华电青岛环保技术有限公司 | 2018-08-17 | — | — | CN | claimed |
| US-9647275-B2 | Bi-functional catalysts for oxygen reduction and oxygen evolution | STC.UNM (US) | 2017-05-09 | — | — | US | claimed |
| CN-105195157-A | Carbon monoxide low-temperature oxidation catalyst | UNIV GUANGDONG PETROCHEM TECH | 2015-12-30 | — | — | CN | claimed |
| US-20150180046-A1 | Bi-Functional Catalysts for Oxygen Reduction and Oxygen Evolution | STC.UNM (US) | 2015-06-25 | — | — | US | claimed |
| WO-2013187976-A1 | BI-FUNCTIONAL CATALYSTS FOR OXYGEN REDUCTION AND OXYGEN EVOLUTION | STC.UNM (US) | 2013-12-19 | — | — | WO | claimed |
| WO-2010000591-A2 | FLUORESCENT CYCLIC PEPTIDES, METHODS FOR THE PREPARATION THEREOF, AND USE OF SAID PEPTIDES FOR MEASURING THE ENZYMATIC ACTIVITY OF A PROTEASE ENZYME | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-01-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250312777-A1 | CUBIC FLUORITE RARE-EARTH HIGH ENTROPY OXIDES AND THEIR CATALYSIS APPLICATIONS | CA13, CA12, CA14 | MEN1 1161/4885KMT2A 3185/4885CA5A 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.