SCHEMBL355949

SCHEMBL355949

OCc1cc2ccccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 1.00
ASIC3 Q9UHC3 1/20 0.64
LOXL2 Q9Y4K0 1/20 0.64
AGXT P21549 1/20 0.58
ADRB2 P07550 1/20 0.58
MGLL Q99685 1/20 0.48
ADRA1D P25100 2/20 0.47
BCL2L1 Q07817 1/20 0.47
IDH1 O75874 1/20 0.45
APP P05067 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzothiophene SCHEMBL7101018 0.88 CYP2A6 (0.77) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL17666748 0.83 CYP2A6 (0.71) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL661546 0.83 CYP2A6 (0.71) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL291668 0.83 CYP2A6 (0.70) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL4961407 0.82 CYP2A6 (0.69) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL79169 0.80 CYP2A6 (0.67) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL18666283 0.78 CYP2A6 (0.64) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL240588 0.78 CYP2A6 (1.00) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL9810053 0.78 CYP2A6 (0.64) CYP2A6ASIC3LOXL2AGXTADRB2
SCHEMBL2568843 0.78 CYP2A6 (0.64) CYP2A6ASIC3LOXL2AGXTADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111548269-B Preparation method of diaryl methane structural compound 兰州大学 2023-10-27 CN claimed
CN-115557836-A Preparation method of carboxylic acid 云南大学 2023-01-03 CN claimed
CN-111548269-A Preparation method of diarylmethane structure compound 兰州大学 2020-08-18 CN claimed
CN-106928121-B High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound 暨南大学 2020-05-12 CN claimed
CN-102797043-B Medicinal molecular fragment library and construction process thereof Tianli (Tianjin) Technology Co., Ltd. (CN) 2015-11-25 CN claimed
CN-102797043-A Medicinal molecular fragment library and construction method thereof CBB NETWORK CO LTD 2012-11-28 CN claimed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 US disclosed
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME KULEON LLC (US) 2025-09-11 US disclosed
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression Kuleon, LLC (US) 2025-07-01 US disclosed
US-12275701-B2 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators Kuleon, LLC (US) 2025-04-15 US disclosed
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION Kuleon, LLC (US) 2025-03-20 US disclosed
US-5183818-A Also for inhibiting leukotriene biosynthesis ABBOTT LABORATORIES (US) 1993-02-02 US disclosed
EP-0496836-A1 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS. RES CORP TECHNOLOGIES INC (US) 1992-08-05 EP disclosed
WO-1991005564-A1 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-05-02 WO disclosed
EP-0401817-A2 Reagents for rapid peptide synthesis RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1990-12-12 EP disclosed
US-4654350-A Gaba-agonistic imidazo(4,5-c)pyridines useful as pharmaceuticals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-03-31 US disclosed
EP-0082369-B1 IMIDAZO (4,5-C) PYRIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION MERCK PATENT GmbH (DE) 1986-04-09 EP disclosed
EP-0082369-A1 Imidazo (4,5-c) pyridines, pharmaceutical compositions containing them and process for their preparation MERCK PATENT GmbH (DE) 1983-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 CYP2A6 242/4885ASIC3 1930/4885LOXL2 1259/4885
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME HTR7, HTR2C, HTR1A CYP2A6 351/4885ASIC3 4242/4885LOXL2 2558/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A CYP2A6 351/4885ASIC3 4242/4885LOXL2 2558/4885
US-12275701-B2 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators HTR2A, HTR2C, HTR1A CYP2A6 1856/4885ASIC3 1892/4885LOXL2 1529/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A CYP2A6 1646/4885ASIC3 1786/4885LOXL2 1544/4885
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression HTR2A, HTR2C, HTR3A CYP2A6 1179/4885ASIC3 927/4885LOXL2 2822/4885
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION HTR2A, HTR2C, HTR3A CYP2A6 1179/4885ASIC3 927/4885LOXL2 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.