Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551155 | 0.86 | HTR6 (0.46) | LMNAMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL3558811 | 0.84 | MAPT (0.53) | LMNAHTTMEN1TSHRKMT2A | |
| SCHEMBL3563355 | 0.83 | SLC16A3 (0.61) | F2SLC16A3FABP4NMT1AVPR1B | |
| SCHEMBL3567099 | 0.81 | CA12 (0.59) | FABP4LMNAHTTMEN1TSHR | |
| SCHEMBL3555109 | 0.80 | SLC16A3 (0.57) | F2SLC16A3FABP4NMT1AVPR1B | |
| SCHEMBL3558720 | 0.79 | L3MBTL1 (0.61) | FABP4LMNAUSP2CPT1ACPT1B | |
| SCHEMBL3555623 | 0.78 | WDR5 (0.52) | F2FABP4NMT1TSHR | |
| SCHEMBL3559952 | 0.78 | ALDH1A1 (0.51) | SLC16A3PFKFB4MEN1KMT2A | |
| SCHEMBL3561566 | 0.78 | CYP19A1 (0.61) | LMNAHTTMEN1TSHRKMT2A | |
| SCHEMBL16509566 | 0.78 | NMT1 (0.62) | F2NMT1AVPR1BLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | F2 608/4885SLC16A3 425/4885FABP4 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.