SCHEMBL3564647

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3559203	0.96	SIGMAR1 (0.56)	MEN1KMT2ASIGMAR1HRH3HRH1
	SCHEMBL3558558	0.96	SIGMAR1 (0.56)	MEN1KMT2ASIGMAR1HRH3HRH1
	SCHEMBL1723767	0.88	HRH3 (0.54)	SIGMAR1HRH3HRH1HRH2
	SCHEMBL491704	0.84	HRH3 (0.64)	MEN1KMT2AHRH3HRH1HRH2
	SCHEMBL7246784	0.82	HRH3 (0.63)	HRH3HRH1HRH2
	SCHEMBL9590450	0.82	TRPV4 (0.43)	TRPV4
	SCHEMBL9591627	0.82	TRPV4 (0.43)	TRPV4
	SCHEMBL9345940	0.82	TRPV4 (0.43)	TRPV4HRH3HRH1HRH2
	SCHEMBL9346410	0.82	TRPV4 (0.43)	TRPV4
	SCHEMBL3564027	0.82	CHEK1 (0.50)	TRPV4SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.