Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.49 |
| ▸ | TUBB | P07437 | 4/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555901 | 0.86 | HTR2A (0.58) | HTR6HTR7HTR1AHTR1DSLC6A4 | |
| SCHEMBL3553981 | 0.85 | PDE10A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3563594 | 0.84 | HTR6 (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3558001 | 0.82 | HTR7 (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3564365 | 0.81 | SLC6A4 (0.43) | HTR6HTR7HTR1AHTR1DSLC6A4 | |
| SCHEMBL3555171 | 0.78 | PDE10A (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL855097 | 0.77 | TNKS (0.50) | HTR6HTR7HTR1AHTR1DSLC6A4 | |
| SCHEMBL3462480 | 0.77 | SLC6A4 (0.42) | HTR6HTR7SLC6A4CYP1A2CYP2C9 | |
| SCHEMBL3564100 | 0.75 | HTR7 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL23876044 | 0.72 | HTR7 (0.49) | HTR6HTR7HTR1AHTR1DSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |
| US-7718690-B2 | N-arylsulfonyl-3-aminoalkoxyindoles | RAMAKRISHNA VENKATA SATYA NIROGI | 2010-05-18 | — | — | US | disclosed |
| US-20090131507-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131507-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | HTR3C, HTR3A, AANAT | TUBB4A 1964/4885TUBB 1549/4885TUBA3C 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.