SCHEMBL3565632

SCHEMBL3565632

CC(C)(C)c1cc(-c2ccccc2)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
RARB P10826 1/20 0.57
RARG P13631 1/20 0.57
ALDH1A1 P00352 4/20 0.55
ALOX15 P16050 3/20 0.55
LMNA P02545 2/20 0.55
HTT P42858 2/20 0.55
HSD17B10 Q99714 2/20 0.55
NR1I2 O75469 1/20 0.55
CYP2C9 P11712 1/20 0.55
MIF P14174 1/20 0.55
TYR P14679 1/20 0.55
NFE2L2 Q16236 1/20 0.55
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KDM4E B2RXH2 3/20 0.52
MAPT P10636 2/20 0.52
ESR2 Q92731 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28521094 0.96 RARB (0.54) ALOX5RARBRARGALDH1A1ALOX15
SCHEMBL16581393 0.90 ALDH1A1 (0.57) ALOX5RARBRARGALDH1A1ALOX15
SCHEMBL31146788 0.89 ALDH1A1 (0.67) RARBRARGALDH1A1ALOX15LMNA
SCHEMBL1176397 0.89 ALDH1A1 (0.67) RARBRARGALDH1A1ALOX15LMNA
SCHEMBL9167807 0.87 ALDH1A1 (0.57) ALOX5RARBRARGALDH1A1ALOX15
SCHEMBL1237149 0.86 ALDH1A1 (0.69) ALOX5RARBRARGALDH1A1ALOX15
SCHEMBL2721125 0.86 ALDH1A1 (0.69) ALOX5RARBRARGALDH1A1ALOX15
Biphenyl SCHEMBL28011227 0.85 ALDH1A1 (0.53) ALOX5RARBRARGALDH1A1ALOX15
Biphenyl SCHEMBL28492519 0.85 ALDH1A1 (0.53) ALOX5RARBRARGALDH1A1ALOX15
SCHEMBL6878804 0.84 ALOX5 (0.57) ALOX5RARBRARGALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957152-B Synthesis method of benzoxazole compound 湖南第一师范学院 2023-11-17 CN claimed
CN-114957152-A Synthetic method of benzoxazole compound 湖南第一师范学院 2022-08-30 CN claimed
EP-0852486-A2 ANTIPLAQUE ORAL COMPOSITION Colgate-Palmolive Company (US) 1998-07-15 EP claimed
US-5723500-A WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-03-03 US claimed
WO-1997010800-A2 ANTIPLAQUE ORAL COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1997-03-27 WO claimed
CN-114957152-B Synthesis method of benzoxazole compound 湖南第一师范学院 2023-11-17 CN disclosed
CN-114957152-A Synthetic method of benzoxazole compound 湖南第一师范学院 2022-08-30 CN disclosed
US-20210299095-A1 METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE CASE WESTERN RESERVE UNIVERSITY 2021-09-30 US disclosed
CN-112293502-A Carbon quantum dot antioxidant, preparation method thereof and application thereof in frying oil 江南大学 2021-02-02 CN disclosed
US-7842825-B2 Biaryloxymethylarenecarboxylic acids as glycogen synthase activator HOFFMANN-LA ROCHE INC. (US) 2010-11-30 US disclosed
US-7700632-B2 Biaryloxymethylarenecarboxylic acids as glycogen synthase activator HOFFMANN-LA ROCHE INC. (US) 2010-04-20 US disclosed
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
EP-0518241-B1 Hydroformylation process and bisphosphite compound used therein MITSUBISHI CHEM CORP (JP) 1996-09-11 EP disclosed
US-5446213-A Dimerizing lower olefin in presence of catalyst containing nickel compound, organic aluminum compound, specified alkyl substituted phenyl phosphite MITSUBISHI KASEI CORPORATION (JP) 1995-08-29 US disclosed
EP-0518241-A2 Hydroformylation process and bisphosphite compound used therein Mitsubishi Chemical Corporation (JP) 1992-12-16 EP disclosed
US-4247427-A Adhesion promoted block copolyester composition with multi-functional carboxylic compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-27 US disclosed
US-4156702-A Adhesion promoted block copolyester composition with multi-functional carboxylic compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-05-29 US disclosed
US-4107138-A Phosphonous and thiophosphonous acid ethers as stabilizers for organic materials SANDOZ LTD. (CH) 1978-08-15 US disclosed
US-4048128-A ALKALINE EARTH OXIDE, POLYCARBODIIMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-13 US disclosed
US-3969294-A Segmented copolyester adhesives stabilized by alkaline earth oxides and carboxylic compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299095-A1 METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE RRM2, RRM2B, RRM1 ALOX5 887/4885RARB 154/4885RARG 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.