Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084982 | 0.84 | ALDH1A1 (0.34) | HPGDALDH1A1HSD17B10HTTKDM4E | |
| SCHEMBL7073731 | 0.81 | ALDH1A1 (0.37) | MAPTHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL7088428 | 0.81 | ALDH1A1 (0.42) | LMNANPC1GAAMAPTRAB9A | |
| SCHEMBL9466305 | 0.81 | NAAA (0.46) | LMNACHRM4HPGDALDH1A1KDM4E | |
| SCHEMBL9465986 | 0.81 | NAAA (0.46) | LMNACHRM4HPGDALDH1A1KDM4E | |
| SCHEMBL22263190 | 0.80 | KDM4E (0.43) | GAAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL7482755 | 0.79 | KDM4E (0.44) | NPC1RAB9ACHRM4HPGDALDH1A1 | |
| SCHEMBL23810117 | 0.79 | — | — | |
| SCHEMBL7084568 | 0.76 | ROCK2 (0.37) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL11003607 | 0.74 | NPC1 (0.40) | LMNANPC1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696355-B2 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20070232670-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | disclosed |
| US-7157481-B2 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-02 | — | — | US | disclosed |
| US-20050159464-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2005-07-21 | — | — | US | disclosed |
| US-6875783-B2 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2005-04-05 | — | — | US | disclosed |
| US-20040044054-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2004-03-04 | — | — | US | disclosed |
| US-6642181-B2 | 3,4-dichloro-isothiazole-5-carboxamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-04 | — | — | US | disclosed |
| US-20020091067-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2002-07-11 | — | — | US | disclosed |
| US-6372692-B1 | PESTICIDES, FUNGICIDES, INSECTICIDES, NEMATOCIDES, AND MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-16 | — | — | US | disclosed |
| US-6277791-B1 | PREVENT PLANT DAMAGE; FUNGICIDE, BACTERICIDE, VIRICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159464-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, AADAC, CBR3 | LMNA 4856/4885NPC1 1354/4885GAA 779/4885 |
| US-20070232670-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, AADAC, CBR3 | LMNA 4856/4885NPC1 1354/4885GAA 779/4885 |
| US-20020091067-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, CBR3, AADAC | LMNA 4852/4885NPC1 719/4885GAA 921/4885 |
| US-20040044054-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, CBR3, AADAC | LMNA 4852/4885NPC1 719/4885GAA 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.