Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13515535 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HTTKDM4EHPGDMAPK1 | |
| SCHEMBL7084568 | 0.84 | ROCK2 (0.37) | ALDH1A1HTTKDM4EHPGDMAPK1 | |
| SCHEMBL3566444 | 0.84 | LMNA (0.42) | ALDH1A1HTTKDM4EHPGDMAPK1 | |
| SCHEMBL22263190 | 0.82 | KDM4E (0.43) | ALDH1A1HTTKDM4EHPGDMAPK1 | |
| SCHEMBL7088428 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HTTKDM4EHPGDMAPK1 | |
| SCHEMBL7073731 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HTTKDM4EHPGDMAPK1 | |
| SCHEMBL7482755 | 0.77 | KDM4E (0.44) | ALDH1A1HTTKDM4EHPGDMAPK1 | |
| SCHEMBL9465986 | 0.76 | NAAA (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9466305 | 0.76 | NAAA (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7088251 | 0.73 | HPGD (0.43) | ALDH1A1HTTKDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | NIHON BAYER AGROCHEM, K.K. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1261592-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001055124-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | IFNG, MPO, CD14 | ALDH1A1 430/4885HTT 4571/4885KDM4E 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.