Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581360 | 0.85 | MCL1 (0.40) | SLC2A1MCL1LMNAHPGDMEN1 | |
| SCHEMBL3576227 | 0.85 | ALDH1A1 (0.37) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3578656 | 0.84 | MCL1 (0.37) | SLC2A1MCL1LMNAHPGDMEN1 | |
| SCHEMBL3583628 | 0.79 | MCL1 (0.40) | SLC2A1MCL1LMNAHPGDMEN1 | |
| SCHEMBL27750941 | 0.78 | MCL1 (0.37) | MCL1LMNAHPGDMEN1KMT2A | |
| SCHEMBL3582291 | 0.78 | MCL1 (0.39) | SLC2A1MCL1LMNAHPGDMEN1 | |
| SCHEMBL3573789 | 0.78 | LMNA (0.41) | SLC2A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL3583039 | 0.77 | CNR1 (0.43) | MCL1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3577275 | 0.77 | MCL1 (0.39) | SLC2A1MCL1LMNAHPGDMEN1 | |
| SCHEMBL3579273 | 0.77 | LMNA (0.37) | MCL1LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |