Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577052 | 0.92 | C5AR1 (0.37) | CNR1UTS2RMCL1C5AR1LMNA | |
| SCHEMBL3578978 | 0.91 | CNR1 (0.43) | CNR1C5AR1LMNAMEN1CYP1A2 | |
| SCHEMBL27730385 | 0.88 | LMNA (0.43) | CNR1UTS2RMCL1C5AR1LMNA | |
| SCHEMBL3579938 | 0.85 | MAPT (0.42) | CNR1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3580876 | 0.85 | LPAR1 (0.36) | CNR1C5AR1ATMSMN1; SMN2RCE1 | |
| SCHEMBL3589192 | 0.84 | PPARA (0.39) | C5AR1SMN1; SMN2RCE1 | |
| SCHEMBL3581360 | 0.84 | MCL1 (0.40) | CNR1MCL1LMNAMEN1CYP1A2 | |
| SCHEMBL3580698 | 0.84 | C5AR1 (0.44) | CNR1UTS2RC5AR1LMNAMEN1 | |
| SCHEMBL3583296 | 0.82 | LPAR1 (0.52) | C5AR1RCE1 | |
| SCHEMBL27730382 | 0.80 | C5AR1 (0.39) | CNR1UTS2RMCL1C5AR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |