Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 4/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3568221 | 0.85 | SLC2A1 (0.36) | SMN1; SMN2CYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL3571182 | 0.85 | C5AR1 (0.41) | ALDH1A1SMN1; SMN2C5AR1LPAR1LPAR5 | |
| SCHEMBL3578978 | 0.81 | CNR1 (0.43) | SMN1; SMN2C5AR1LPAR1LPAR5RCE1 | |
| SCHEMBL3583296 | 0.80 | LPAR1 (0.52) | C5AR1LPAR1LPAR5RCE1 | |
| SCHEMBL3589192 | 0.80 | PPARA (0.39) | ALDH1A1SMN1; SMN2C5AR1LPAR1LPAR5 | |
| SCHEMBL3583039 | 0.80 | CNR1 (0.43) | SMN1; SMN2C5AR1RCE1LSSCYP1A2 | |
| SCHEMBL3577052 | 0.79 | C5AR1 (0.37) | ALDH1A1SMN1; SMN2C5AR1LPAR1LPAR5 | |
| SCHEMBL3580876 | 0.78 | LPAR1 (0.36) | ALDH1A1SMN1; SMN2C5AR1LPAR1LPAR5 | |
| SCHEMBL3579938 | 0.74 | MAPT (0.42) | SMN1; SMN2LPAR1LPAR5RCE1MEN1 | |
| SCHEMBL3576432 | 0.73 | C5AR1 (0.43) | ALDH1A1C5AR1LPAR1LPAR5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |