Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085619 | 0.86 | ALDH1A1 (0.54) | MEN1KMT2ANPC1RAB9AEPHX1 | |
| SCHEMBL5175711 | 0.86 | ALDH1A1 (0.51) | MEN1KMT2ARAB9AEPHX1ALDH1A1 | |
| SCHEMBL4530051 | 0.78 | ROCK2 (0.52) | CNR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27744394 | 0.78 | ROCK2 (0.52) | CNR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3942501 | 0.77 | EPHX1 (0.50) | CNR1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7971029 | 0.75 | CYP2C19 (0.47) | MEN1CYP1A2CYP2C19KMT2APOLB | |
| SCHEMBL2738906 | 0.75 | CYP2C19 (0.47) | MEN1CYP1A2CYP2C19KMT2APOLB | |
| SCHEMBL15577692 | 0.74 | ALDH1A1 (0.46) | CYP2C19KMT2AEPHX1ALDH1A1 | |
| SCHEMBL10431760 | 0.74 | NPC1 (0.48) | CNR1MEN1CYP2C19KMT2ANPC1 | |
| SCHEMBL3277780 | 0.73 | MEN1 (0.45) | CNR1MEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |