SCHEMBL357189

SCHEMBL357189

CN(C)CCNC(=O)C(N)Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.51
PKM P14618 1/20 0.51
PTGS1 P23219 1/20 0.51
XIAP P98170 1/20 0.51
SLC7A5 Q01650 1/20 0.51
ANPEP P15144 2/20 0.50
RNPEP Q9H4A4 2/20 0.50
DNPEP Q9ULA0 2/20 0.50
LAP3 P28838 3/20 0.49
CTSC P53634 1/20 0.49
MMP2 P08253 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
SLC15A1 P46059 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6895415 0.99 ALPI (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8895410 0.92 LAP3 (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL21010316 0.86 SLC15A1 (0.64) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL9554672 0.84 MMP8 (0.52) CYP3A4TSHR
SCHEMBL3577970 0.83 KIF11 (0.46)
SCHEMBL3577967 0.83 KIF11 (0.46)
SCHEMBL20328084 0.83 TLR2 (0.44) ANPEPRNPEPDNPEPMMP2
SCHEMBL5873365 0.83 MMP2 (0.60) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL5873362 0.83 MMP2 (0.60) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL5873359 0.83 MMP2 (0.60) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120015372-A1 METHODS AND COMPOSITIONS FOR PATHOGEN DETECTION USING FLUORESCENT POLYMER SENSORS UNIVERSITY OF MASSACHUSETTS (US) 2012-01-19 US disclosed
US-20120015372-A1 METHODS AND COMPOSITIONS FOR PATHOGEN DETECTION USING FLUORESCENT POLYMER SENSORS UNIVERSITY OF MASSACHUSETTS (US) 2012-01-19 US disclosed
US-8021891-B2 Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-09-20 US disclosed
US-8021891-B2 Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-09-20 US disclosed
US-8021891-B2 Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-09-20 US disclosed
US-8003404-B2 Methods and compositions for pathogen detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-08-23 US disclosed
US-8003404-B2 Methods and compositions for pathogen detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-08-23 US disclosed
US-8003404-B2 Methods and compositions for pathogen detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-08-23 US disclosed
US-20100021960-A1 Methods and compositions for pathogen detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-01-28 US disclosed
US-20100021960-A1 Methods and compositions for pathogen detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-01-28 US disclosed
US-20100021960-A1 Methods and compositions for pathogen detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-01-28 US disclosed
US-20090221099-A1 Methods and compositions for protein detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 US disclosed
US-20090221099-A1 Methods and compositions for protein detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 US disclosed
US-20090221099-A1 Methods and compositions for protein detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 US disclosed