Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622159 | 0.91 | TSHR (0.42) | CDK2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3570859 | 0.89 | MAPK10 (0.38) | MEN1KMT2AGAASMN1; SMN2MAPK8 | |
| SCHEMBL3562691 | 0.85 | MAPK10 (0.52) | CCNA2CDK2LMNAKDM4EL3MBTL1 | |
| SCHEMBL3566255 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL3558059 | 0.76 | MEN1 (0.34) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL3565626 | 0.75 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3569022 | 0.74 | GPR39 (0.41) | CDK2MEN1KMT2A | |
| SCHEMBL3572008 | 0.73 | SMN1; SMN2 (0.35) | CDK9MAPTMEN1KMT2ALMNA | |
| SCHEMBL3562759 | 0.72 | CDK9 (0.40) | CCNT1CDK9MAPTMEN1KMT2A | |
| SCHEMBL3566316 | 0.72 | AXL (0.41) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855212-B2 | Pyridinyl acetonitriles | MERCK SERONO SA (CH) | 2010-12-21 | — | — | US | claimed |