Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.33 |
| ▸ | UBE2M | P61081 | 6/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584408 | 0.92 | MEN1 (0.39) | LMNACNR1DCUN1D1UBE2MS1PR1 | |
| SCHEMBL3583120 | 0.87 | GRM2 (0.37) | LMNACNR1DCUN1D1UBE2MPIM1 | |
| SCHEMBL3580280 | 0.83 | DCUN1D1 (0.36) | LMNACNR1DCUN1D1UBE2MS1PR1 | |
| SCHEMBL3576637 | 0.83 | LMNA (0.41) | LMNACNR1PIM1PDGFRAS1PR1 | |
| SCHEMBL3586114 | 0.82 | LMNA (0.41) | LMNACNR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL3581091 | 0.80 | STAT3 (0.39) | CNR1DCUN1D1UBE2MMCHR1 | |
| SCHEMBL3583574 | 0.80 | HSD11B1 (0.34) | LMNADCUN1D1UBE2MS1PR1S1PR5 | |
| SCHEMBL27730361 | 0.79 | LMNA (0.33) | LMNACNR1MCHR1MEN1CYP1A2 | |
| SCHEMBL3574585 | 0.78 | LMNA (0.42) | LMNACNR1PIM1PDGFRAS1PR1 | |
| SCHEMBL3573419 | 0.78 | GRM2 (0.39) | LMNADCUN1D1UBE2MS1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |